Senior Scientist, Analytical Sciences

Alnylam Pharmaceuticals • Cambridge, MA

1d • Onsite

About The Position

Analytical Development at Alnylam is seeking a highly motivated Senior Scientist with expertise in Bioassay including cell-based assays using different cell types and detection formats, qPCR, ELISA . This role involves performing non-GMP in-house Bioassay method development, testing while supporting and overseeing method development , GMP testing at external laboratories. In this role, you will be an individual contributor.
This is a full time, onsite position based in Cambridge, MA.

Requirements

• Ph.D. in a scientific discipline with 5 years of experience in biotechnology or pharmaceutical laboratory is required.
• Strong expertise including hands-on experience with cell-based assays, ELISA, and qPCR.
• Robust understanding of regulatory guidance and industry standards relevant to bioassay related CMC activities, particularly in the development and validation of bioassays.
• Strong scientific, analytical problem solving and communication skills are required.
• Demonstrate adaptability and a willingness to support changing priorities and evolving departmental needs
• Highly organized, detail-oriented and computer proficiency to handle related scientific tasks.
• Ability to work independently in a fast pace work environment and prioritize several projects with minimal supervision.
• Flexibility to travel to CTLs\CMOs on an as needed basis.

Nice To Haves

• Experience with microbiological tests preferred.

Responsibilities

• Perform and oversee cell based assays including ELISA and qPCR as well as microbiology tests.
• Lead feasibilities, development and transfers for cell based assays internally and externally, building and maintaining key relationships at CTLs.
• Apply deep knowledge of regulatory guidelines (ICH, USP chapters) to ensure compliance in bioassay development and validation as well as data verification.
• Provide bioassay technical leadership within assigned programs and offer guidance across other programs as needed.
• Draft, review and/or approve protocol, reports, certificates of testing.
• Record results of analysis in electronic notebook and/or in appropriate documentation method.
• Participate in cross-functional training and facilitate continuous improvement.
• Provide training and mentorship to colleagues and junior scientists within this area of expertise.

Benefits

• We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match.
• Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.
• We also offer generous family resources and leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree