Senior Scientific Lead - Translational Sciences

Eli Lilly • Indianapolis, IN

395d • $135,000 - $211,200

About The Position

The Senior Scientific Lead at Lilly will be part of the Translational Sciences group, focusing on precision medicine in oncology. This role involves designing and executing experiments, managing in vivo studies, and collaborating with clinical teams to advance cancer therapies. The position requires a strong understanding of molecular and cell biology, with a hands-on approach in a laboratory environment.

Requirements

• PhD in Molecular/Cellular Biology or Biochemistry, or related field and 6+ years hands-on molecular and cell biology experience OR a BS/MS in Molecular/Cellular Biology or Biochemistry and 10+ years hands-on molecular and cell biology experience.
• Strong understanding of cell cycle and signal transduction pathways.
• Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels.
• Highly organized with excellent analytical, documentation and multi-tasking skills.

Nice To Haves

• Work experience in a biotech/pharma setting preferred.
• Extensive experience in developing and running cellular assays; engineering cell lines to express or knock-down/knock-out genes of interest.
• Experience with general molecular biological techniques including q-PCR, ELISA, assays for protein-protein interactions and Western Blot etc.
• Experience in experimental curve-fitting and statistics helpful.
• Experience in building up models (cell line, organoid or PDX) from patient samples and using them to test drug activities.
• Committed to staying current with the latest scientific breakthroughs in the targeted oncology field from target identification through human clinical trials.
• Enthusiastic, self-motivated and keen to improve processes and overcome inefficiencies.

Responsibilities

• Design and execute key experiments to evaluate compounds, identify combination partners and investigate drug resistance.
• Design and manage in vivo studies.
• Translate preclinical findings to biomarker and combination strategies to advance programs to clinical development.
• Work closely with clinical team to develop and test hypotheses that could determine the clinical response and define the patient populations.
• Engage in cross-functional collaborations across the company.
• Identify, evaluate, and manage vendors for outsourced services and studies.
• Prepare reports for internal and external purposes including regulatory submissions.
• Participate and lead project-based and technical team meetings to identify and solve problems, guide work towards project goals, communicate on-going work and progress, and plan forward thinking strategies.

Benefits

• Eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Bachelor's degree