Senior Research Technologist - Horbinski Lab

Mayo Clinic • Jacksonville, FL

119d

About The Position

The Horbinski Lab is dedicated to advancing brain tumor research through innovative preclinical modeling of gliomas and meningiomas, as well as developing cutting-edge molecular biomarkers from both tissue and liquid biopsies. We are seeking a highly skilled and motivated Senior Research Technologist to join our team. The Senior Research Technologist will serve as a specialist in molecular biology, leading projects involving advanced genomic and epigenomic assays while also contributing expertise in animal models. This hybrid skillset will make the individual a key resource for bridging bench-based molecular work with preclinical modeling.

Requirements

• Requires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience
• Strong track record of hands-on experience in sequencing library preparation and other advanced molecular assays
• Working knowledge of animal models, including tumor xenografts, with a solid understanding of compliance requirements
• Proven ability to mentor junior staff and uphold high standards of accuracy and reproducibility
• Excellent problem-solving skills, adaptability, and collaborative mindset

Nice To Haves

• Master's degree in biology, chemistry, or other relevant science preferred
• Degree in molecular biology, genetics, cancer biology, or a related field (Masters preferred)

Responsibilities

• Independently sets up and performs experiments and procedures in support of lab goals and grant commitments (e.g. assays, cell/tissue culture, animal studies, etc.)
• Contributes to the planning, design and modification of studies and experiments in the research lab setting
• Monitors results, reports unusual outcomes and suggests modifications
• Collects, enters, summarizes, and analyzes data
• May oversee and assist with the training of residents, fellows and temporary lab personnel in lab techniques
• Lead biomarker studies requiring advanced sequencing technologies
• Prepare sequencing libraries for whole genome, methylation, and RNA-based assays
• Drive adoption and optimization of emerging platforms, including Nanopore sequencing
• Ensure quality control and reproducibility across molecular experiments
• Apply hands-on experience with mice, including handling, injections, and monitoring for tumor xenograft studies
• Assist with in vivo experimental design and contribute to IACUC protocol preparation
• Collaborate with in vivo specialists to integrate animal studies with molecular analyses
• Train and supervise Research Technologists in both molecular and animal techniques
• Work closely with the Principal Research Technologist and PI to align molecular biology efforts with overall research goals
• Contribute to troubleshooting, data interpretation, and the development of new protocols

What This Job Offers

• Career Level: Mid Level
• Industry: Hospitals
• Education Level: Bachelor's degree