Senior Research Scientist, Metabolism and Toxicokinetics

Corteva Agriscience • Newark, DE

4d • Onsite

About The Position

Corteva Agriscience™ is seeking an experienced Senior Research Scientist to provide scientific and technical leadership in metabolism and toxicokinetics in support of crop protection product discovery and global regulatory registration. Based at the Haskell R&D Center in Newark, Delaware, this role will lead the design, execution, interpretation, and reporting of in vitro and in vivo ADME and toxicokinetic studies. The successful candidate will serve as a subject matter expert in the support of human health safety assessments of crop protection products. What you’ll do: Design, interpret, and report results for discovery (non-GLP) and regulatory (GLP) studies in toxicokinetics or ADME (absorption, distribution, metabolism, and excretion) to advance the crop protection chemical discovery and registration pipelines. Provide subject matter expertise for the ADME sciences within the Global Regulatory Sciences function on cross-functional discovery and development project teams. Provide technical leadership and coaching to junior scientific staff. Communicate findings to business and scientific audiences, through both oral presentations and written technical reports and manuscripts.

Requirements

• Ph.D. in pharmacokinetics, toxicology, or related area with at least five years of relevant experience. Or, BS or MS degree in related discipline with minimum 15 years relevant experience.
• Demonstrated experience and expertise in the design of in vitro (e.g., hepatocyte/metabolic stability, plasma protein binding) and in vivo (e.g., rodent metabolism and mass balance) ADME studies.
• Thorough knowledge and expertise in xenobiotic metabolism, clearance mechanisms, absorption, and toxicokinetics.
• Demonstrated teamwork and leadership abilities to manage and coordinate multiple projects and chemistries in a timely and effective manner.
• Strong written and oral communication skills that allow dissemination of complex technical issues in a clear, concise manner to a variety of scientific and non-scientific audiences.

Nice To Haves

• Experience as a study director working in a GLP (Good Laboratory Practice) environment, preferably in industry or CRO.
• Experience working safely with radioactivity, including carbon-14.
• Experience using commercial pharmacokinetic and physiologically based kinetic (PBK) modeling software (e.g. Phoenix® WinNonlin®, GastroPlus®).
• Track record of impactful publications in ADME, PBK modeling, or toxicology

Responsibilities

• Design, interpret, and report results for discovery (non-GLP) and regulatory (GLP) studies in toxicokinetics or ADME (absorption, distribution, metabolism, and excretion) to advance the crop protection chemical discovery and registration pipelines.
• Provide subject matter expertise for the ADME sciences within the Global Regulatory Sciences function on cross-functional discovery and development project teams.
• Provide technical leadership and coaching to junior scientific staff.
• Communicate findings to business and scientific audiences, through both oral presentations and written technical reports and manuscripts.

Benefits

• Numerous development opportunities offered to build your skills
• Be part of a company with a higher purpose and contribute to making the world a better place
• Health benefits for you and your family on your first day of employment
• Four weeks of paid time off and two weeks of well-being pay per year, plus paid holidays
• Excellent parental leave which includes a minimum of 16 weeks for mother and father
• Future planning with our competitive retirement savings plan and tuition reimbursement program
• Learn more about our total rewards package here - Corteva Benefits
• Check out life at Corteva! www.linkedin.com/company/corteva/life

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees