Senior Research Associate

University of Colorado•Aurora, CO

14d•$77,000•Onsite

About The Position

This position will focus on understanding the molecular mechanism of pre-mRNA splicing and its role in disease processes. Candidates will be expected to plan and execute independent experiments, write and publish experimental results, help with lab daily operation, contribute to grant writing, and contribute positively towards the atmosphere and culture of the lab. Our department conducts research across a wide biological scale for fundamental scientific understanding with applications to many disease contexts. The overarching goal is to reach a level of molecular insight that helps develop therapeutic approaches to disease. As biochemists and molecular geneticists, we are amid an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.

Requirements

PhD in biology-related field
Strong record of productivity as evidenced by peer-reviewed publications in internationally recognized journals
Experience in molecular biology, cell culture, and biochemical techniques.
Knowledgeable in molecular biology, biochemistry, and cell biology.
Highly motivated, have ample scientific curiosity, have strong interpersonal skills, and be able to contribute in a positive manner to the collegial atmosphere of the laboratory and the department.
Be able to conduct independent research, and mentor more junior lab members.

Nice To Haves

Prior research experience in RNA biology especially pre-mRNA splicing or structural biology especially cryo-EM is highly desired.

Responsibilities

Design and implement molecular biology, biochemical, cell biology, and structural experiments to understand the mechanism of pre-mRNA splicing, the structure and function of spliceosome and its components, and how to modulate splicing in disease process using small molecules.
Prepare manuscript for publication.
Present scientific at various seminars and meetings.
Help with lab daily operation such as supply ordering.
Contribute to grant writing.