Senior Research Associate, Pharmacology

Flagship Pioneering•Cambridge, MA

1d•$81,000 - $107,250

About The Position

FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases. FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture. We are searching for a motivated Sr. Research Associate to drive in vivo studies for platform development and therapeutic proof-of-principle. More broadly, we are looking for an individual who enjoys working with animal models and brings scientific rigor, intellectual curiosity, enthusiasm, and a desire to innovate new nucleic acid therapeutics. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment, working as part of a highly collaborative and rapidly growing team.

Requirements

BS with 5+ or MS in relevant discipline with 3+ years of industry experience.
Experience executing in vivo studies, ideally involving gene delivery and/or nucleic acid based therapeutics in rodents.
Experience dosing therapeutics via intravenous, intraperitoneal, intramuscular, and subcutaneous routes of administration.
Experience collecting materials (blood, tissue, etc.) and supporting processing and execution of ex vivo bioanalytics.
Strong communication and interpersonal skills.
Demonstrated ability to work effectively in a team environment, working closely cross-functionally to achieve shared objectives.
Strong organizational, analytical, and problem-solving skills.
Strong understanding of the scientific method and its application in a biotech setting to drive development and innovation with data rigor
Welcome new challenges and maintain productivity and quality in a high-energy, rapidly growing biotech environment.

Nice To Haves

Experience with various rodent models of diseases is a plus.

Responsibilities

Execute and analyze animal experiments to assess in vivo efficacy, safety, and PK/PD profiles of novel nucleic acid therapeutics.
Support the design and execution of method development and pilot experiments to test specific hypotheses and drive R&D efforts with guidance.
Maintenance of electronic lab notebooks and timely documentation of data
Provide support in additional in vitro assays as needed.
Ensure rapid documentation of all results and observations without compromising data integrity or scientific accuracy.
Effectively communicate experimental findings in oral, written, and visual formats.
Work independently and collaboratively in a multidisciplinary team environment.