(CW) Senior Research Associate – Formulation & Analytical Support

BioMarin Pharmaceutical Inc.•San Rafael, CA

24d•Onsite

About The Position

BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best – people with the right technical expertise and a relentless drive to solve real problems – and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we’ve produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our R&D engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. CONTRACT ROLE Position is on-site 5 days a week in San Rafael We are seeking a highly skilled Senior Research Associate to provide formulation and analytical support for oligonucleotide based therapeutics across in vitro and in vivo studies. This individual will work both independently and collaboratively to ensure high quality dosing solutions, execute stability testing, support analytical workflows, and contribute to nonclinical and clinical development programs.

Requirements

Good understanding of oligonucleotide therapeutics, formulation approaches, and stability testing
Hands on experience with analytical techniques such as UV spectroscopy, LC MS, and osmolality measurements
Ability to perform quantitative analysis across studies with minimal supervision
Demonstrated ability to work independently while contributing effectively within cross functional teams
Strong problem solving skills and attention to detail
Bachelor’s degree in Chemistry, Pharmaceutical Sciences, Biochemistry, or a related field with 6+ years of relevant experience, or
Master’s degree with 4+ years of relevant experience

Responsibilities

Independently and collaboratively prepare, formulate, and quality check dosing solutions for a range of in vitro and in vivo studies
Perform formulation stability studies and define appropriate short and long term storage conditions
Support formulation strategies for oligonucleotides across different delivery and study paradigms
Execute analytical assays to support formulation and quality assessment, including UV, LC MS, and osmolality measurements
Perform quantitative data analysis across multiple experiments, including basic statistical and graphical analysis
Proactively troubleshoot technical issues and recommend corrective actions to ensure data quality and project continuity
Develop new techniques or introduce new technologies to enhance the group’s formulation and analytical capabilities
Contribute to continuous improvement of laboratory workflows and experimental approaches
Maintain accurate and thorough laboratory notebook records in compliance with data integrity standards
Prepare SOPs, technical reports, and documentation to support nonclinical and clinical programs, including regulatory submissions
Present data and actively participate in group meetings, department meetings, and Early Development team meetings
Share responsibility for laboratory management duties, including equipment readiness, inventory, and general lab organization