Senior Research Associate, Cardiometabolic Discovery

Flagship Pioneering•Cambridge, MA

11d•$81,000 - $107,250

About The Position

Quotient Therapeutics Ltd is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need. The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). We are an equal opportunity employer. We are seeking a motivated and creative Senior Research Associate to join our team focused on performing in vitro studies to characterize novel somatic variants in the context of Cardiometabolic disease. This role requires a strong background in life sciences to execute experiments that investigate somatic variant function to validate potential drug targets. The position involves a combination of hands-on lab work, data analysis, and scientific communication to ensure a target's potential benefit for a disease. The successful candidate will be a self-starter, able to thrive in a fast-paced, action-oriented team environment.

Requirements

Master’s degree in life sciences, biotechnology, biology, or related field with 0-2 years of relevant experience in industry
Bachelor’s degree in life sciences, biotechnology, biology, or related field with 2-4 years of relevant experience in industry
Hands-on experience with cell culture, molecular biology and protein techniques (academic or industry settings)
Ability to manage multiple tasks, work independently, and thrive in a collaborative team environment
Familiarity with electronic lab notebooks (ELNs) or related data-management tools
Must possess a high degree of flexibility and adaptability to evolving job requirements and priorities
entrepreneurial spirit
strong communication skills
comfort in working in and contributing to a dynamic and cross-functional team environment

Nice To Haves

Preferred experience in organoid/spheroid primary cell culture systems with steatosis and fibrosis readouts

Responsibilities

Perform a variety of laboratory experiments, including cell-based assays, molecular biology techniques, and sometimes in vivo studies, to validate new targets and test drug candidates
Utilize techniques such as RNA purification, qPCR, ELISA and Western blotting to analyze cellular and molecular responses
Assist in the design and optimization of research protocols to validate therapeutic targets
Collect, analyze, and interpret scientific data, with a strong ability to use tools like Excel and GraphPad Prism
Maintain a detailed and up-to-date electronic lab notebook and write high quality experimental protocols
Work in a team-oriented environment, sharing findings and collaborating with other scientists