Senior Project Manager - Oncology/Hematology (Phase III)

Syneos Health, Inc • Morrisville, NC

39d

About The Position

As a Senior Project Manager, you will take a lead role in advancing Phase III Oncology and Hematology clinical trials, managing complex, global initiatives. You'll lead and inspire cross-functional teams, mentor emerging project managers, and act as the primary strategic partner for our clients, ensuring every milestone is delivered on time, on budget, and with exceptional quality. This role offers the opportunity to drive high-impact research that directly contributes to innovative cancer therapies and improved patient outcomes worldwide.

Requirements

• Experienced Global Project Leader (NA, LATAM, EMEA, and APAC) with strong Phase III CRO project management experience and a proven track record of delivering clinical trials successfully.
• Oncology and Hematology expertise, with direct experience leading complex Phase III trials.
• Cross-functional team leadership, overseeing such teams as Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and Quality Assurance.
• Financially savvy, skilled in managing multi-million-dollar budgets, including creation, forecasting, and negotiation of out-of-scope work.
• Vendor management expertise, ensuring alignment, quality, and accountability across all study partners.
• Deep regulatory knowledge, with expertise in GCP/ICH guidelines and other applicable regulatory requirements.
• Educational foundation: Bachelor's degree in Life Sciences, Medicine, Pharmacy, Nursing, or a related field.
• Tech-forward, comfortable leveraging digital tools and emerging technologies to optimize project delivery.
• Strategic, results-driven leader with exceptional communication skills, able to navigate complex, dynamic environments while inspiring teams to achieve excellence.

Responsibilities

• Drive the operational and financial success of Phase III clinical trials.
• Lead cross-functional teams across Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, Medical Affairs, Pharmacovigilance, and QA.
• Act as the primary liaison with clients, ensuring smooth project launch, conduct, and closeout.
• Oversee project deliverables, timelines, and budgets while proactively identifying and mitigating risks.
• Mentor junior project managers and project support staff, fostering collaboration and professional growth.
• Own project budgets, forecasts, and financial performance.
• Ensure alignment and accountability across all vendors and study partners.
• Implement contingency plans and risk mitigation strategies to keep projects on track.
• Maintain and evaluate project progress using advanced tracking tools.
• Prepare and present project materials for internal and external stakeholders.
• Support inspection readiness and Trial Master File compliance.
• Participate in bid defense meetings as the potential project lead.
• Build strong client relationships to generate new opportunities.
• Stay up-to-date on oncology/hematology trends and the evolving drug development landscape.
• Train and mentor new project managers and clinical staff.
• Facilitate team communication, collaboration, and professional development.

Benefits

• The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Professional, Scientific, and Technical Services
• Number of Employees: 5,001-10,000 employees