Senior Principal Software Engineer

Roche

80d • $189,200 - $270,300

About The Position

Our team is composed of forward-thinking scientists, engineers, and researchers who are passionate about revolutionizing healthcare through innovation. We are seeking a highly motivated and experienced Software Engineer to join our growing team and contribute to the development of high-performance, high-quality NGS bioinformatics algorithms. As a Software Engineer specializing in Next Generation Sequencing Bioinformatics at Roche Diagnostics, you will play a critical role in designing, developing, and optimizing cutting-edge algorithms to extract meaningful insights from genomic data. This position offers a unique opportunity to work on innovative projects that impact the fields of diagnostics and precision medicine. You will work closely with cross-functional teams of biologists, data scientists, and software engineers to build robust, scalable, and efficient software solutions.

Requirements

• Bachelor's or higher degree in Computer Science, Bioinformatics, Computational Biology, or a related field.
• At least 8-10 years of proven experience in developing high quality software and algorithms for NGS data analysis.
• Strong proficiency in programming languages such as C++ and Python.
• A track record of proficiency in relevant bioinformatics tools and libraries.
• Demonstrated progression in experience with parallel computing, optimization, and performance tuning.
• Strong problem-solving skills and attention to detail.
• Excellent communication and teamwork skills.

Nice To Haves

• Experience working in a regulated environment (e.g., FDA, CLIA).
• Experience with GPU development and optimization.

Responsibilities

• Design and implement high-performance algorithms for NGS data analysis, including variant calling, quality control, and data preprocessing.
• Continuously refine and optimize bioinformatics solutions for handling large-scale genomic datasets with improved efficiency and performance.
• Partner with biologists, data scientists, and engineers to meet the unique challenges of NGS diagnostics and research workflows.
• Seamlessly incorporate bioinformatics tools into Roche's software ecosystem, ensuring compatibility and robustness.
• Maintain the integrity of analytical results by crafting rigorous test suites and working alongside QA teams.
• Stay at the forefront of NGS and bioinformatics trends while mentoring junior engineers and driving innovation within the company.

Benefits

• Discretionary annual bonus based on individual and Company performance.

What This Job Offers

• Education Level: Bachelor's degree
• Number of Employees: 5,001-10,000 employees