Senior Principal Biostatistician

Novartis • Cambridge, MA

72d • $119,700 - $222,300

About The Position

Within the Quantitative Sciences Drug Development function, the Advanced Methodology and Data Science pillar plays a crucial role in enhancing analytical capabilities to support drug development and regulatory decision-making. This Principal / Senior Principal position focuses on optimizing approaches for data-driven decision-making, utilizing clinical study data along with other internal and external data sources.

Requirements

• PhD in statistics, biostatistics, data science or another related field with 3+ years' experience preferred.
• Knowledge in relevant quantitative approaches.
• Fluent English (oral and written).
• Strong communication and presentation skills.

Responsibilities

• Develop and apply sophisticated models to optimize study design, analyze complex datasets, and enhance predictive capabilities.
• Explore and implement novel statistical techniques such as Bayesian modeling, statistical learning, machine learning, and causal inference.
• Conduct flexible, rapid-response analyses to address emerging scientific and regulatory questions.
• Work closely with Biostatistics, Pharmacometrics, Statistical Programming, and drug development teams to enhance study design, data interpretation, and evidence generation strategies.
• Identify recurring problems and use a combination of reproducible research techniques and tool development to provide scalable, reusable solutions.
• Contribute to internal education and awareness efforts in quantitative science.
• Collaborate with regulatory, academic, and industry partners to advance drug development science through innovative quantitative approaches.
• Publish in peer-reviewed journals, organize sessions at professional conferences, and contribute to cross-industry workstreams and external scientific working groups.

Benefits

• Comprehensive benefits package including health, life and disability benefits.
• 401(k) with company contribution and match.
• Generous time off package including vacation, personal days, holidays and other leaves.
• Performance-based cash incentive.
• Eligibility for annual equity awards.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree