Senior Medical Director, Medical Affairs

Intellia Therapeutics, Inc.•Cambridge, MA

2d•$295,965 - $361,735•Remote

About The Position

Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together. As the Medical Affairs Senior Medical Director for the NTLA-2001 ATTR amyloid polyneuropathy program, you embrace the challenge to create an innovative US and global Medical Affairs approach to support Intellia’s CRISPR/cas9 programs. This individual has a history of clinical and pharmaceutical industry experience, ideally in the fields of neuropathic disorders, with a specialty in neurology being preferred. The candidate will also have strong experience in product launches, including proven ability to translate and appropriately align commercial and medical goals and objectives. This role will be responsible for developing and leading medical affairs plans in close collaboration with cross-functional teams, contributing to clinical strategy, collaborating to develop impactful medical education, evidence generation and healthcare system and key stakeholders engagement plans. In addition, the Senior Medical Director for the NTLA-2001 ATTR amyloid polyneuropathy program will be accountable for operational oversight of execution of the plans.

Requirements

Robust clinical research experience within the pharmaceutical/biotech industry
Previous experience leading a medical affairs/clinical development team with responsibility for late-stage clinical studies across multiple regions
Solid communication, strategic, interpersonal, and negotiating skills, with ability to proactively predict challenges and solve problems
Ability to drive decision-making within a multi-disciplinary, multi-regional, matrix teams
Diplomacy and positive influencing abilities
Knowledge of both regional and global Regulatory requirements
Track record of successful and emerging research in therapeutic areas relevant to Intellia’s development programs and pipeline
Demonstrated ability to present complex issues to management and contribute to executive level presentations and discussions
Experience leading and motivating cross-functional teams and vendors/consultants
Excellent interpersonal skills with an ability to respond to multiple external and internal queries, managing and handling conflict constructively
Success working in a fast paced, matrixed, growing organization, partnering with multiple internal & external stakeholders
MD/PharmD
At least 10 years experience in Medical Affairs and Clinical Development in the biotechnology/pharmaceutical industry
Experience in Medical Affairs leadership for products addressing rare diseases, with strong therapeutic area knowledge relevant to mechanism of action of NTLA-2001.

Nice To Haves

ideally in the fields of neuropathic disorders, with a specialty in neurology being preferred

Responsibilities

Medical Affairs Product Lead for NTLA-2001 ATTR-PN, our lead investigational therapy for the treatment of transthyretin amyloidosis in patients with polyneuropathy, in the development of short-term and long-term strategy, as well as execution of the program medical affairs plan as a key component of the integrated brand plan and in full support of the key strategic imperatives
Lead the Medical Access Commercial subteam for NTLA-2001 ATTR-PN, together and in close partnership with the Medical Affairs Lead and Program Brand Lead
Responsible for the alignment of all global medical affairs activities in close partnership with other members of the Medical Access Commercial subteam and Program Leadership Team
Responsible for the medical accuracy and fair balance of medical information in educational and other medical communication and learning materials for both internal and external use.
Collaborate with other line functions (Clinical Development, HEOR, etc.) to ensure that the medical evidence generation plan is aligned with the NTLA-2001 ATTR-PN program objectives
Develop and drive strategic engagement plan with stakeholders identified as strategic partners, including advocacy groups, medical societies, payers, and provider groups as well as medical experts in ATTR amyloid polyneuropathy, especially in the United States
Work closely with Patient Advocacy, Medical Engagement and Regional Scientific Directors to develop and execute medical engagement strategy
Plan and execute on holding of national and regional medical advisory boards with the ATTR-PN community
Provide medical input into the safety profile of the product in collaboration with Clinical Development and Patient Safety (PS) colleagues
Collaborate with all Medical Affairs functions and work closely with Access & HEOR to support key educational, engagement and evidence generation initiatives
Provide clinical support to the design and execution of HEOR studies, outcomes surveys, etc. in close collaboration with HEOR/Access colleagues
Work closely with Clinical Development team to ensure optimal collaboration and inclusion of external clinicians/KOLs and other relevant healthcare system stakeholders in clinical trial planning, enrollment, and interpretation
Develop relationships and drive interactions with investigators, KOLs, research institutions, and centers of excellence to oversee and support the ATTR-PN Medical Affairs plan
Collaborate with the Scientific Communications team supporting the review and approval of publications and resources ensuring medical accuracy and alignment of all communication materials
Lead Intellia Medical Affairs initiatives at key congress meetings and conferences, including content development and presentation for internal and external medical education programs as needed