Senior Manager Technology Prosper Center

Children’s Hospital of Philadelphia•Philadelphia, PA

About The Position

The PROSPER (PRecisiOn perSonalized PEdiatric psychiatRy) Center at CHOP is a cross-disciplinary initiative dedicated to transforming pediatric mental health care through ethically grounded, data-driven, and AI solutions. This leadership role will lead the Center's technical strategy and ensure its alignment with larger enterprise systems, clinical operations, and translational goals. The Senior Manager of Technology will work closely with clinicians, data scientists, software engineers, clinical investigators, implementation specialists, and institutional partners to advance the development and deployment of AI-powered tools and multimodal data pipelines across research and care delivery settings.

Requirements

Master's Degree Computational Biology, Computer Science, Information Science, Informatics, Biomedical Engineering or a related discipline - Required
At least eight (8) years Experience leading technical teams or projects focused on data science, AI/ML tools, or clinical decision support systems - Required
At least five (5) years Experience supervising interdisciplinary teams across technical, clinical, and research domains - Required
At least ten (10) years Designing and deploying secure, scalable, and interoperable data platforms or software in healthcare or research settings - Required
At least seven (7) years Developing and validating machine learning models, clinical algorithms, or computational pipelines - Required
Expertise in HIPAA, IRB, and ethical considerations for use of clinical data in research and innovation Required (Required proficiency)
Strong understanding of AI/ML principles, model evaluation, and clinical integration strategies Required (Required proficiency)
Demonstrated success translating technical concepts to diverse stakeholders including clinicians and leadership Required (Required proficiency)
Track record of leading cross-functional teams to build and scale research infrastructure or digital tools Required (Required proficiency)

Nice To Haves

Knowledge of responsible AI practices and health equity in technology design and deployment Preferred (Required proficiency)
Experience aligning research computing systems with enterprise informatics or cloud infrastructure Preferred (Required proficiency)

Responsibilities

Foster a culture of innovation, collaboration, and continuous learning within the technology team within the PROSPER center.
Manage and mentor a multidisciplinary team of AI researchers, data scientists, and IT professionals.
Define and oversee the technical architecture for PROSPER’s research and innovation infrastructure, including multimodal data integration, algorithm deployment, and secure computing environments.
Align and follow best practices as defined by the Cloud Center of Excellence lead by CHOP’s CTO and the Director of Cloud Products.
Build to the standards of the Enterprise application team to ensure software meets the standard and can be deployed in clinical settings (e.g., containerized and version controlled, security vulnerability assessment).
Guide the evaluation and adoption of advanced technologies including AI/ML pipelines, real-time data feeds (e.g., EHR, sensors), and federated analytics tools.
Support the development and operationalization of PROSPER’s core tools, such as risk-resilience calculators for waitlist prioritization and prediction models for clinical decision-making.
Establish standards for tool development Continuous Integration and Continuous Development (CICD), code standards (eg PEP8 or
Establish best practices for algorithm evaluation, documentation, and user feedback in partnership with clinical and community stakeholders.
Provide mentorship and technical guidance to PROSPER and affiliated staff and trainees, including data scientists, engineers, and research fellows.
Engage in cross-functional collaboration with clinical investigators, ethicists, and implementation scientists to ensure clinical tools are practical, equitable, and sustainable.
Serve as a key member of the PROSPER Center’s leadership team, contributing to strategic planning, infrastructure growth, and research prioritization.
Liaise with institutional and external partners to position PROSPER as a leader in applied clinical data science and AI innovation in pediatric healthcare.
Manage direct reports with hire/fire and performance evaluation responsibilities.
Provide mentorship and technical guidance to PROSPER and affiliated staff and trainees, including data scientists, engineers, and research fellows.