Senior Manager, Scientific Programming

BeiGene • Cambridge, MA

6d

About The Position

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. Position Summary: We are seeking a highly skilled Real-World Data (RWD) Programmer to join the Scientific Programming team. The successful candidate will lead programming activities to support real-world evidence (RWE) generation using large-scale healthcare data sources (e.g., electronic health records, claims, registries). This role will collaborate with biostatistics and technical teams to implement and deliver high-quality analytic datasets, outputs, and visualizations.

Requirements

• Strong proficiency in R and SQL (Python and SAS experience a plus) or other data manipulation languages to manage and analyze large-scale healthcare datasets.
• Basic knowledge of statistical analysis methodologies and study design concepts
• Fundamentals of project planning and management
• Drug development process
• Excellent verbal and written communication skills
• Excellent problem-solving skills and ability to work independently and collaboratively in a fast-paced environment
• Ability to effectively collaborate in a dynamic environment
• Master’s degree, in Computer Science, Statistics, Mathematics, Life Sciences or other relevant scientific subjects, or equivalent related experience
• Minimum 7+ years’ clinical research and development programming experience using R and SQL.
• Minimum 5+ years’ RWD programming experience in healthcare analytics settings using R and SQL.

Nice To Haves

• Expert level R and SQL programmer with demonstrated experience in handling large-scale healthcare datasets and delivering on complex programming assignments and analysis
• Deep knowledge of real-world data sources (claims, EHRs, registries) and observational study design
• Strong understanding of healthcare coding systems (ICD, CPT, NDC, HCPCS, RxNorm)
• Experience in supporting HEOR, epidemiology or medical affairs teams
• Experience in Oncology studies
• Experience leading or working with centralized teams for Statistical Programming
• Experience in FDA/EMEA/CFDA trial and regulatory submissions
• Experience in development and implementation of statistical programming standards and procedures
• Experience with the drug development process (pre-, early, late and/or observational) in related industries or academic research.
• Experience with oncology trials.
• Expert level SAS programmer with experience in delivering complex programming assignments and analysis.
• Proficient in developing their own code as well as modifying existing code.

Responsibilities

• Develop, validate and maintain analysis-ready datasets, tables, figures and listings for observational and RWE studies derived from diverse real-world data sources, including claims, electronic health records (EHRs) and registry data
• Write, test and validate programs to produce analysis datasets, TLFs and presentation output, to be included in reports for submission to regulatory agencies, publications and other communications as needed
• Conduct exploratory data analyses to support evidence generation, feasibility assessments and study design refinement
• Interact and communicate with programming teams and stakeholders to identify efficient programming solutions and contribute to analytic strategy
• Manage and contribute to the standardization and automation of data processing workflows, including the development of reusable programming templates and data refreshes
• Design and develop effective visualizations and interactive dashboards (e.g. Power BI, Spotfire, R-Shiny) to support decision-making
• Apply best practice in RWD programming and analytics to develop and deliver high-quality reports independently
• Understand and execute department-, product- and study-level macros and utilities. Write, test and validate product- and study-level macros and utilities
• Be a technical resource for programming teams to provide advice on complex programming tasks and/or standards
• Contribute to the development review of Statistical Programming policies, standard operating procedures and other controlled documents
• Interface with outsourcing partners and vendors
• Other duties as assigned

Benefits

• All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan.
• The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees