Senior Infrastructure Architect

Kymera Therapeutics • Watertown, MA

102d

About The Position

Kymera Therapeutics is seeking a highly skilled Infrastructure Architect to join our Infrastructure & Operations team as a key partner to the Senior Director. This role will serve as the number two within the team, with a primary focus on designing, implementing, and optimizing our cloud and network infrastructure. The ideal candidate will bring deep expertise in both AWS and Azure environments, combined with enterprise networking and identity management experience. This role is critical in shaping Kymera’s technology landscape — evaluating the current environment, defining the target state, and executing on a strategic roadmap to enable scientific innovation and business growth. A particular emphasis will be placed on securely moving and integrating data from on-premises laboratory equipment into AWS, while also strengthening hybrid identity, endpoint management, and cloud governance.

Requirements

• 8+ years of progressive experience in IT infrastructure roles, with at least 3 years in an architecture or senior engineering capacity.
• Proven expertise in AWS architecture, design, and operations (AWS Solutions Architect Professional certification strongly preferred).
• Strong background in enterprise networking (firewalls, VPN, routing, switching, hybrid/cloud connectivity, SD-WAN).
• Experience integrating on-premises data sources and lab environments with cloud platforms.
• Solid knowledge of Azure and Entra ID hybrid identity management, including Conditional Access, authentication, and governance.
• Hands-on experience with Intune for endpoint compliance, configuration, and security.
• Familiarity with infrastructure as code (Terraform, CloudFormation, or equivalent).
• Strong problem-solving, communication, and stakeholder engagement skills.
• Experience in biotech, pharma, or research-intensive organizations is a plus.

Responsibilities

• Partner with the Senior Director of Infrastructure & Operations to define and execute the strategic roadmap for infrastructure and cloud services.
• Architect, implement, and manage scalable AWS environments to support research, development, and business applications.
• Design and maintain secure and reliable enterprise networking, including firewalls, routing, switching, hybrid connectivity, and dual internet connections.
• Develop strategies for reliable and secure transfer of lab data into AWS, leveraging AWS best practices for compliance and scalability.
• Consult on Azure and Entra ID (Azure AD) hybrid identity initiatives, including Conditional Access, authentication policies, and governance.
• Oversee Intune endpoint management, including device compliance, configuration policies, and security baselines.
• Collaborate with Security, Applications, and Data teams to ensure end-to-end solution integrity and compliance.
• Provide hands-on technical leadership, including architecture design, proof-of-concepts, and implementation oversight.
• Mentor team members and contribute to building a high-performing infrastructure and operations organization.

What This Job Offers

• Number of Employees: 101-250 employees