Senior Generative AI Engineer

Natera

6d • $125,000 - $156,300 • Remote

About The Position

The Senior Generative AI Engineer is responsible for designing, building, and deploying Natera’s Generative AI and Machine Learning solutions. The role needs excellent hands-on AI engineering excellence to build robust, accurate, and reliable AI solutions. This role requires deep expertise in Generative AI and machine learning engineering at scale, with a passion for building solutions that directly impact patient outcomes and clinical innovation.
In this role, you will develop enterprise-grade AI/ML solutions that power internal workflows (R&D, Lab Ops, Clinical Trials, Billing, Patient/Provider engagement) to automate business processes.
You will also build cutting-edge AI solutions leveraging agentic architecture, retrieval-augmented generation (RAG), vector search, feature stores, LLMOps, experimentation, observability, and compliance-first AI pipelines.

Requirements

• 8+ years of experience in software engineering, ML engineering, or applied AI
• Proven experience building and operating LLM-based systems in production
• Strong Python skills and experience with PyTorch and/or Hugging Face
• Experience building agentic AI solutions using agent frameworks (LangChain, CrewAI etc.) and agent execution engines (AWS Bedrock etc.)
• Solid understanding of RAG architectures, embeddings, vector databases, and prompt orchestration
• Experience deploying AI systems on AWS (e.g., SageMaker, Bedrock, EKS/ECS, Lambda, S3)
• Strong debugging skills and comfort working across model, data, and infrastructure layers
• Ability to work independently on complex problems and communicate clearly with cross-functional partners

Nice To Haves

• Masters degree or PhD in Computer Science, AI/ML, engineering or related field
• Experience in healthcare, pharma, diagnostics, or other regulated industries
• Familiarity with AI governance frameworks, bias detection, explainability, and compliance (e.g., HIPAA, CLIA, FDA)

Responsibilities

• Design, build, and operate LLM-powered systems used in production, from initial design through deployment and iterations
• Build scalable agentic AI automation solutions, selecting appropriate patterns (reasoning, memory, agent frameworks, MCP’s, workflow orchestration, fine-tuning) based on business requirements
• Implement GenAI patterns such as RAG, tool/function calling, and multi-step workflows, selecting approaches based on accuracy, reliability and cost
• Develop and maintain data ingestion and retrieval pipelines, especially for unstructured or semi-structured documents
• Fine-tune and adapt open-source or commercial LLMs for domain-specific tasks when appropriate
• Set quality, evaluation, and reliability standards for GenAI systems, including testing, monitoring, observability, and failure handling
• Make system-level tradeoffs across model choice, latency, cost, accuracy, and operational complexity, and guide teams through those decisions
• Deploy and monitor GenAI services on AWS, optimizing for latency, cost, and system stability
• Collaborate with product managers and domain experts to translate requirements into technical solutions
• Establish golden paths (templates, examples, docs) and contribute to shared GenAI libraries, patterns, and best practices used by other engineers
• Provide technical guidance and mentorship to mid-level engineers

Benefits

• Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
• Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
• Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
• We also offer a generous employee referral program!

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Number of Employees: 1,001-5,000 employees