Senior Director/Vice President, Medical Affairs

Braveheart Bio•San Francisco, CA

18d•$330,000 - $400,000

About The Position

The Senior Director/Vice President of Medical Affairs will serve as Braveheart’s senior medical leader and a key architect of the medical strategy supporting the global development and future launch of BHB-1893 for hypertrophic cardiomyopathy (HCM). This individual will shape and execute a comprehensive medical affairs roadmap spanning late-stage development, launch readiness, and lifecycle planning. A core responsibility of this role is building trusted scientific partnerships with the global HCM community—including key opinion leaders, investigators, and patient advocacy groups—to strengthen external engagement and support meaningful scientific exchange. This individual will also provide leadership and oversight for all medical activities to ensure they reflect the highest standards of scientific integrity and remain fully compliant with regulatory and industry guidelines. As Braveheart grows, the Senior Director/VP of Medical Affairs will build and lead the medical affairs function, establishing the people, processes, and systems needed to support Phase 3 execution, data generation, launch planning, and post-approval medical excellence.

Requirements

MD preferred; Ph.D. or PharmD in a relevant scientific discipline may also be considered
Clinical background in cardiovascular medicine, ideally including HCM or heart failure experience
At least 5 years of medical affairs experience in biotechnology or pharmaceuticals, ideally supporting competitive brands or complex specialty products
Strong clinical and scientific judgment, with the ability to translate data into actionable medical and strategic insights
Demonstrated success building and leading teams in a matrixed, cross-functional environment
Excellent communication and interpersonal skills with the ability to engage credibly with internal and external stakeholders
Ability to work independently and collaboratively in a fast-moving, resource-lean environment
Proven ability to manage multiple priorities and deliver high-quality outputs under tight timelines
Commitment to excellence, continuous learning, adaptability, and proactive problem-solving
Strong written and verbal communication skills with a collaborative, team-oriented approach
Ability to thrive in a fast-paced, dynamic environment and remain comfortable with change and ambiguity
Flexible, proactive, and hands-on mindset with a roll-up-your-sleeves, can-do attitude

Responsibilities

Develop and drive the global medical affairs strategy and tactical plan for BHB-1893 in alignment with Braveheart’s overall development and commercial objectives
Build and lead a high-performing medical affairs organization, including medical communications, medical information, publications, and field medical capabilities
Cultivate strong relationships with key external stakeholders such as clinicians, scientific leaders, advocacy groups, payers, and regulatory bodies
Provide medical governance and ensure all external-facing medical activities and materials comply with applicable laws, regulations, and industry standards
Oversee development and delivery of scientific training, medical education, and medical information resources
Lead the publication and scientific communication strategy to support data dissemination and evidence transparency
Contribute medical insight into protocol development, evidence generation planning, and interpretation of clinical data
Represent Braveheart at scientific congresses, advocacy meetings, and key partnership discussions
Serve as a medical strategic partner to the Commercial team, providing clinical insight for content development, messaging, and launch readiness activities
Maintain deep awareness of the scientific and competitive landscape to inform strategy and position BHB-1893 effectively