Senior Director, Operations Commercialization Lead (Cell Therapy)

AstraZeneca • Gaithersburg, MD

17d • Hybrid

About The Position

Position Overview The Senior Director, Operations Commercialization Lead will establish AstraZeneca's global supply chain commercialization and roadmap for cell therapy products. Drive the development of go-to-market operational strategies, optimizing supply chain efficiency,, cost, and long term success across clinical development, commercial launch, and product lifecycles. You will be based in Gaithersburg, MD and will report to the Head, Cell Therapy Global Supply Chain. You Will: Supply Chain Strategic Leadership· Lead formation and delivery of commercial supply strategic roadmap for cell therapy, ensuring seamless integration of supply with commercial operations. Align strategic programs with cross-functional partners to achieve mutual financial, service-level, and outcome-based goals. Represent Cell Therapy Operations on the Global Product Teams that commercialize and increase cell therapy products across the Oncology, Biopharm and Alexion departments. Collaboration & Stakeholder Engagement Partner with commercial and operations responsibilities to ensure strategies and operational plans foster innovation, efficiency, and shared success across the value chain. Be a main interface between the Commercial Business Units and the Cell Therapy Organization, aligning supply chain go-to-market plans with commercial and product strategy, including assessments and recommendations for investment decisions and market expansion business cases. Value Chain Design & Launch Leadership Design, and increase end-to-end value chains for new products and throughout the product lifecycle, focusing on scalability, and regulatory compliance. Promote capability development with functional leaders, supporting supply chain, commercial operations goals, and financial goals. Lead commercial launch activities, aligning Product, Commercial, and Operations, to accomplish commercial launches. Lead end-to-end coordination of cross-functional teams to deliver launch success and global supply chain orchestration. Identify process gaps and risks across the supply chain, developing business continuity plans to avoid supply disruption. You Have: Bachelor's degree in life sciences, engineering, or supply chain required; advanced degree (MBA, MS) 14+ years of experience in biopharma operations, with at least 2 (two) years in advanced therapies (cell and gene therapy). 12+ years with advanced degree. Experience with autologous and allogeneic supply models and global supply chain management in the cell therapy, biologics, or pharmaceutical sector A comprehensive understanding of product development, manufacturing and supply management within a matrixed environment Understanding of global, regional and local environments to identify risks, and design supply chains. Experience in leadership of cross-functional teams for new product introduction and commercial launches Mastery of value chain design, S&OP/IBP, procurement and logistics. Think, strategy development, project management, business case development, financial skills, product costing capabilities. Demonstrated proficiency in stakeholder management and executive-level communication to effectively influence senior leaders across the organization. Proven capability in leading cross-functional teams and navigating complex matrix organizational structures Our Benefits: Benefits offered included a qualified retirement program [401(k) plan]; Paid vacation and holidays; paid leaves; and, health benefits including medical. Prescription drug, dental, and vision coverage following the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. #CellTherapy #LI-hybrid The annual base pay for this position ranges from $174,756 to $262,134. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program.If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender, gender identity or expression, or veteran status. We are proud to be an equal opportunity workplace. Date Posted 11-Dec-2025 Closing Date 04-Jan-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Requirements

• Bachelor's degree in life sciences, engineering, or supply chain required; advanced degree (MBA, MS)
• 14+ years of experience in biopharma operations, with at least 2 (two) years in advanced therapies (cell and gene therapy). 12+ years with advanced degree.
• Experience with autologous and allogeneic supply models and global supply chain management in the cell therapy, biologics, or pharmaceutical sector
• A comprehensive understanding of product development, manufacturing and supply management within a matrixed environment
• Understanding of global, regional and local environments to identify risks, and design supply chains.
• Experience in leadership of cross-functional teams for new product introduction and commercial launches
• Mastery of value chain design, S&OP/IBP, procurement and logistics.
• Think, strategy development, project management, business case development, financial skills, product costing capabilities.
• Demonstrated proficiency in stakeholder management and executive-level communication to effectively influence senior leaders across the organization.
• Proven capability in leading cross-functional teams and navigating complex matrix organizational structures

Responsibilities

• Lead formation and delivery of commercial supply strategic roadmap for cell therapy, ensuring seamless integration of supply with commercial operations.
• Align strategic programs with cross-functional partners to achieve mutual financial, service-level, and outcome-based goals.
• Represent Cell Therapy Operations on the Global Product Teams that commercialize and increase cell therapy products across the Oncology, Biopharm and Alexion departments.
• Partner with commercial and operations responsibilities to ensure strategies and operational plans foster innovation, efficiency, and shared success across the value chain.
• Be a main interface between the Commercial Business Units and the Cell Therapy Organization, aligning supply chain go-to-market plans with commercial and product strategy, including assessments and recommendations for investment decisions and market expansion business cases.
• Design, and increase end-to-end value chains for new products and throughout the product lifecycle, focusing on scalability, and regulatory compliance.
• Promote capability development with functional leaders, supporting supply chain, commercial operations goals, and financial goals.
• Lead commercial launch activities, aligning Product, Commercial, and Operations, to accomplish commercial launches.
• Lead end-to-end coordination of cross-functional teams to deliver launch success and global supply chain orchestration.
• Identify process gaps and risks across the supply chain, developing business continuity plans to avoid supply disruption.

Benefits

• Benefits offered included a qualified retirement program [401(k) plan]; Paid vacation and holidays; paid leaves; and, health benefits including medical.
• Prescription drug, dental, and vision coverage following the terms and conditions of the applicable plans.
• Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Number of Employees: 5,001-10,000 employees