Senior Director, Global Tuberculosis

Clinton Health Access Initiative

17h•Remote

About The Position

The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization dedicated to saving lives and reducing the burden of disease in low- and middle-income countries. Founded in 2002 to address the HIV/AIDS epidemic by reducing drug prices and increasing access, CHAI has since expanded its focus to include infectious diseases like COVID-19, malaria, tuberculosis, and hepatitis, as well as non-communicable diseases such as cancer, diabetes, and hypertension. The organization also works on accelerating vaccine rollout, reducing maternal and child mortality, combating chronic malnutrition, and increasing access to assistive technology. CHAI strengthens health systems through programs in human resources for health, digital health, and health financing, with a strategy centered on maximizing sustainable impact at scale, ensuring government leadership, national program scalability, and global knowledge sharing. CHAI is a diverse team operating in 40 countries, with most staff based in program countries, and is committed to equal employment opportunities, diversity, and inclusion. Tuberculosis is the world's deadliest infectious disease, causing over 10 million illnesses and 1.2 million deaths annually, predominantly in sub-Saharan Africa and South/Southeast Asia. CHAI's Global TB Program partners with governments, multilateral organizations, and suppliers to address critical gaps in TB care across three interconnected domains: screening and diagnosis (e.g., digital chest X-ray with AI, near-point-of-care molecular diagnostics), treatment and prevention (e.g., shorter regimens, community-based delivery of preventive therapy), and market shaping (e.g., price reductions, generic product development, sustainable supply). The program operates in 13 countries, with the Global TB Team providing strategic direction, technical leadership, and coordination, and managing relationships with key funders and partners. This Senior Director role is pivotal, serving as CHAI's most senior voice on TB, both internally and externally. The individual will define a clear programmatic vision, engage various stakeholders including country teams, donors, and government leaders, and build trust across the complex TB ecosystem. Reporting to the Vice President, HIV, Hepatitis & TB, the Senior Director will be responsible for shaping a portfolio encompassing community-based prevention pilots, diagnostic technology introduction, market shaping interventions, and operational research across multiple countries. The ideal candidate will possess deep TB expertise and a proven track record of delivering sustainable public health impact in low- and middle-income countries, setting a strategic direction that inspires teams and partners to achieve measurable, large-scale impact.

Requirements

12+ years of progressive experience in a related field, with increasing levels of responsibility and leadership.
Strong working knowledge of the global TB landscape, including familiarity with TB epidemiology, diagnostics, therapeutics, and the key donor and policy environment.
Demonstrated success leading global or multi-country programs, with a clear track record of achieving measurable public health impact in low- and middle-income countries.
Outstanding communicator who can distill complex technical and strategic issues into clear, persuasive narratives for varied audiences, and who uses communication deliberately to build consensus, inspire action, and sustain momentum behind a shared vision.
Strong resource mobilization experience, including leading successful proposal development and donor engagement for large, multi-year grants.
Excellent project and people management skills, including designing and managing cross-functional teams spanning multiple geographies and time zones.
Demonstrated high bar for quality, analytical rigor, and attention to detail in programmatic outputs and strategic deliverables.
Track record of building and managing relationships with senior government officials, multilateral organizations, and major institutional donors, with demonstrated ability to align diverse stakeholders around a common agenda and maintain productive partnerships even when organizational interests do not fully overlap.
Entrepreneurial mindset, with the ability to identify and pursue new opportunities, work independently, and drive initiatives forward in fast-paced, limited-structure environments.
Ability and willingness to travel internationally, 25-30% of the time.

Nice To Haves

Deep expertise in tuberculosis, including thorough knowledge of the global TB policy and financing architecture, health systems delivery, or TB clinical management.
Prior experience working with or within national TB programs, the Stop TB Partnership, the Global Fund, Gates, or Unitaid.
Experience in market shaping, health commodity procurement, or access-to-medicines initiatives in a global health context.
Experience living and working in sub-Saharan Africa, South or Southeast Asia, or other high-TB-burden regions.
Advanced degree in management, public health, science, or other relevant fields a plus.

Responsibilities

Define and communicate a bold strategic direction for CHAI's global TB portfolio, translating organizational priorities, donor expectations, and the evolving needs of high-burden countries into a coherent vision that the team, partners, and governments can rally behind.
Scan the horizon for shifts in TB financing, epidemiology, policy, and the diagnostic and therapeutic pipeline; position CHAI to respond proactively and shape the conversation.
Make disciplined strategic choices about where CHAI should focus, including decisions to scale, pivot, or wind down workstreams based on evidence, impact, and changing conditions.
Develop multi-year programmatic plans, budgets, and performance management systems that drive accountability and continuous improvement across the portfolio.
Champion the translation of evidence and operational learning into scalable, government-led program models. Orient the program at every stage toward government ownership, from design through financing and scale-up, so that impact endures beyond CHAI's engagement.
Lead development and execution of CHAI's TB resource mobilization strategy, ensuring the program has the funding to match its ambition and building resilience against shifts in the global aid landscape.
Identify and pursue non-traditional funding opportunities, making the case for TB investment to new donors and positioning CHAI's TB work within broader global health and development agendas, including the growing interest in AI-enabled health solutions.
Manage major donor relationships and program finances, ensuring high-quality reporting, proactive risk management, and disciplined deployment of resources.
Set the intellectual agenda for CHAI's TB work: define the questions the organization should be asking, identify where conventional approaches are falling short, and push the team to develop stronger answers.
Provide hands-on technical guidance to country and regional teams on complex programmatic, policy, and scientific questions spanning diagnostics, treatment, prevention, and service delivery.
Drive CHAI's TB learning and research agenda, including operational research, impact evaluations, cost-effectiveness analyses, and data-driven refinements to program design, ensuring that findings are translated into action.
Stay ahead of the frontier of TB science and innovation, ensuring CHAI is positioned to move quickly as new screening, diagnostic, and treatment tools emerge.
Represent CHAI at the highest levels of the global TB community, from ministerial meetings to donor convenings to technical forums.
Actively shape how the global community prioritizes, funds, and organizes the TB response, bringing evidence and operational insight to bear on policy and investment decisions.
Strengthen CHAI's positioning as a trusted partner and thought leader in the TB ecosystem, known for evidence-informed approaches and a commitment to practical, scalable solutions.
Build and sustain trusted relationships across a diverse ecosystem of multilateral organizations (WHO, the Global Fund, Stop TB Partnership), bilateral donors, academic institutions, suppliers, implementing partners, and civil society, understanding each partner's priorities and finding productive ways to collaborate toward shared objectives.
Navigate a multi-stakeholder landscape with diplomacy and strategic clarity, identifying opportunities for collective action while ensuring CHAI's distinctive contributions are well understood and valued.
Contribute to shaping the global policy environment for TB, including regulatory pathways, normative guidance, and investment frameworks.
Lead, develop, and grow a diverse, high-performing team, strengthening the team's capabilities over time to keep pace with the program's evolving ambitions.
Provide direct management and mentorship to senior team members, including coaching managers of people, investing in their professional development and enabling them to lead their respective portfolios with confidence and autonomy.
Foster a team culture grounded in intellectual rigour, collaboration, accountability, and continuous learning.
Own the TB program's results. Be accountable not only for how the work is managed but for what it achieves: reductions in undiagnosed TB, expanded preventive treatment coverage, and sustainable improvements in how countries detect, treat, and prevent the disease.
Work in close partnership with CHAI country directors and country-based staff, recognizing that the strongest global strategies are built on the insights, relationships, and operational realities that country teams bring.
Collaborate closely with leaders across CHAI's HIV, Diagnostics, Markets, Health Systems, and AI programs to identify synergies, share learning, and pursue integrated approaches where they strengthen impact.
Contribute to organization-wide initiatives that strengthen CHAI's culture, effectiveness, and ability to adapt to a rapidly changing global health landscape.