Senior Director, Global HR Operations and Systems

Madrigal Pharmaceuticals • Waltham, MA

120d

About The Position

Madrigal Pharmaceuticals, a rapidly growing life sciences company committed to innovation and improving patient outcomes, is seeking a Senior Director, HR Operations and Systems to shape and scale our people operations globally. This high-impact role will serve as a strategic thought partner across the business, with a dual focus on enhancing the employee experience and building a scalable foundation for the future of work. You will lead the design and delivery of global HR operational excellence, data insights, and employee-facing processes leveraging our systems (primarily Workday). The ideal candidate brings a consultative, business-minded approach to HR, understands the unique dynamics of a scaling biotech or life sciences environment, and is energized by the opportunity to shape culture and capability through data and design.

Requirements

• Bachelor’s degree in Human Resources, Business, Data Analytics, or related field; advanced degree preferred.
• 15+ years of progressive HR experience, with at least 5 years leading HR operations in a life sciences or biotech company.
• Proven leadership in implementing and managing Workday globally as the HR system of record.
• Experience supporting international operations and designing globally scalable solutions.

Nice To Haves

• Strategic thinker with a consultative mindset and strong business acumen.
• Exceptional ability to synthesize insights from data and communicate with impact to diverse stakeholders.
• Skilled in change management, process design, and cross-functional collaboration.
• High emotional intelligence and credibility in advising senior leaders.

Responsibilities

• Partner closely with HR, business, and functional leaders to understand evolving business needs and co-create scalable, people-first solutions.
• Anticipate future operational requirements and build frameworks that support a high-growth, global organization.
• Lead the global HR Operations team, ensuring service delivery excellence across regions and functions.
• Build and optimize global processes across the employee journey.
• Ensure consistent, compliant, and culturally relevant HR practices in the U.S. and international markets.
• Establish a robust governance structure for employee data integrity and process adherence.
• Champion a human-centered approach to employee services and touchpoints that drive engagement and simplicity.
• Streamline HR service delivery by leveraging automation and integrated technology.
• Develop global knowledge bases, self-service portals, and process improvements to reduce friction and increase employee satisfaction.
• Lead the development of real-time dashboards and people analytics tools to monitor and drive key metrics.
• Translate complex data into actionable insights that enable smarter decision-making for executives and business partners.
• Advance predictive analytics capabilities and elevate HR’s role as a strategic driver of business outcomes.
• Build HR operational models and systems that scale with the company’s growth trajectory and evolving workforce needs.
• Ensure systems and tools are forward-looking, adaptable, and equipped to support a rapidly changing business landscape.
• Serve as a key Workday leader, ensuring optimization, integrations, and functionality are aligned with future enterprise goals.

Benefits

• Flexible paid time off (PTO)
• Medical, dental, vision, and life and disability insurance

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Bachelor's degree
• Number of Employees: 501-1,000 employees