Pfizer’s industry-leading portfolio of anti- virals - is comprised of Paxlovid and ibuzatrelvir (“ ibuza ”). This new leader will have the opportunity t o concurrently focus on accelerating and reigniting the growth of an in-line brand, while also preparing for launch of a new asset. At launch in the 2021-2022 time - frame , there was tremendous anticipation and unmet need for PAXLOVID as the infection rates swelle d. As the 1 st -to-market oral protease inhibitor for the treatment SARS-CoV-2 , Paxlovid rapidly seized dominant market share leadership, which still holds today . It dwarfed revenue targets and was well on its way to becoming a household name. To date, it’s treated 3M+ patients worldwide. However , the COVID-19 epidemiology evolved following the emergence of the Omicron variant. The ensuing sub-variants were believed to have variable transmission rates, with lower p athogenic ity and virulence, resulting in notably fewer hospitalizations and deaths. This marked the transition of COVID-19 from an epidemic to endemi c. The trend toward fewer and less potent cases was one reason for a sharp drop in Paxlovid prescription volume. T he Paxlovid slowdown was multifactorial. In addition to the epidemiology , the sharp decline in volume is being partially attributed to HCP inertia and patient apathy ( springing from the perception of less severe disease and milder symptoms) , as well as concerns over DDIs and dysgeusia (metallic taste) . A nd, of course, the population at large w as gaining immunity via COVID vaccinations and natural infections, which reduced the addressable patient population. In the aftermath of this raging public health crisis, a deep fatigue set in, particularly amongst HCP s and consumers . All that said, agnostic to the trend in infections, our patient funnel modeling illuminate headroom for growth mid-funnel, specifically in “ patient seeking care” behavior and “HCP treatment rate ”. Ibuza is being developed as a follow-on to Paxlovid, but does not contain ritonavir , whi ch precipitate d DDIs and the dysgeusia . Due to t his favorable product profile , we’ll be evaluating not only the safety and the risk reduction of the composite death/hospital endpoint, but also the impact on symptom alleviation and prevention of post-acute sequelae of COVID. Ibuza’s Ph3 RCT is underway and i s tracking to approval across markets in the 2029-2030 time frame. Interestingly, PAXLOVID has a long runway to LOE, which is slated for 2041. In short, the incoming Senior Director/Global Team Leader for COVID-19 treatmen t will inherit a ~$3B revenue target for 2026, a competitive OpEx budget , and six-to-seven direct reports . In exchange, the new Leader is expected to embrace our franchise purpose to “ensure no eligible high-risk patients are left untreated ” and to champion o u r ambition to further entr ench our market leadership . This role provides an excellent opportunity to shape the commercial potential of both assets. In Global Marketing, we translate science into value for patients. Our remit is to own the strategic direction across the asset lifecycle, ensure long-term value creation and preservation, and drive brand consistency across markets and efficiencies in execution. This role will report to the Vice President, Global Franchise Lea d for (non-obesity ) IM, AV, and Migraine .
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Job Type
Full-time
Career Level
Mid Level
Number of Employees
5,001-10,000 employees