Senior Director, Computational Biology

PacBio • Menlo Park, CA

8d • Onsite

About The Position

PacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health. We are now entering the century of biology and genomics is at the heart of the next revolution. Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the PacBio team. The Senior Director, Computational Biology is responsible for leading development of streamlined informatics solutions for HiFi sequencing data that deliver the best clinical and research genomes, transcriptomes, methylomes and metagenomics solutions. This role requires close collaboration with our customers and the scientific community to continually identify and solve the most impactful genomic problems, and plays a critical role in demonstrating what is possible with PacBio sequencing for both research and diagnostics.

Requirements

• Ph.D. in a computational or biological field (e.g., bioinformatics, genetics, genomics, computer science).
• Demonstrated success building scientific software that is broadly used by the genomics community.
• Track record of leading high-impact scientific collaborations and publications as evidenced by a strong publication record and work leading to widely adopted computational tools and methods.
• Demonstrated ability to drive partnerships in both academia and industry.
• Excellent interpersonal, written, and verbal communication skills, with the ability to engage diverse audiences.
• 5+ years of experience in a leadership role at a senior manager level or higher.
• Experience leading multidisciplinary teams and influencing across organizational boundaries.
• Candidates must have current authorization to work in the United States without the need for present or future sponsorship.

Nice To Haves

• Experience in human genomics, including rare disease and/or cancer applications.
• Experience with long-read sequencing analysis and informatics solutions.
• 8+ years of experience in a leadership role at a senior manager level or higher.
• Experience developing and supporting software and computational tools used in regulated or clinical contexts (e.g. CLIA/CAP, FDA/IVDR, GxP).

Responsibilities

• Lead and mentor a high-performing computational biology organization supporting both research innovation and commercial products.
• Provide strategic guidance to translate customer needs and emerging scientific opportunities into scalable, impactful informatics capabilities.
• Identify and develop opportunities and collaborations which demonstrate new scientific and diagnostic applications for PacBio sequencing.
• Provide scientific and technical leadership across the product lifecycle.
• Partner closely with marketing, R&D, engineering and commercial teams to ensure alignment between scientific innovation and product strategy.
• Foster and lead high-impact collaborations with academic, clinical, and industry partners.
• Represent PacBio informatics and scientific leadership at national and international conferences, workshops, and commercial events.
• Lead development of informatics and computational solutions suitable for regulated clinical environments.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree
• Number of Employees: 501-1,000 employees