The Senior Director, Biostatistics leads a matrixed team of statisticians and other quantitative scientists within the Biostatistics organization, partnering with the Clinical Development Unit-focused statisticians, Biostatistical Engineering, Scientific Insights and Medical Affairs groups within Biostatistics, as well as leadership within Statistical Programming and Data Management, Clinical Sciences, Imaging, Precision Medicine, Digital Medicine, R&D, and other key scientific functions at Regeneron. The incumbent is an experienced leader, passionate drug developer, skilled manager and mentor, and an accomplished statistician with a strong ability to communicate technical concepts to non-statisticians. The Senior Director is responsible for providing critical input to novel quantitative strategies that improve decision making for clinical-stage compounds, including but not limited to leveraging multiple measurement modalities (e.g. Imaging, biomarkers) in decision making, developing novel endpoints to quantify drug effects, and modeling disease progression to understand when and how to treat patients. The incumbent is accountable for conceptualizing and executing on quantitative approaches to solve these drug development problems. The Senior Director is also a leader within the Biostatistics and Data Management (BDM) organization and assists/leads in the development and implementation of departmental scientific policies, operational guidelines, and administrative structure. This role is also responsible for project staffing and for appropriate resource allocation consistent with corporate priorities.