Senior Associate Scientist

Pfizer • Andover, MA

4d • Onsite

About The Position

Why Patients Need You Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. At the core of this mission is Research and Development, where we strive to transform advanced science and cutting-edge technologies into the most impactful therapies and vaccines. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, your role is crucial. You will leverage innovative design and process development capabilities to accelerate the delivery of best-in-class medicines to patients globally. This commitment to excellence drives us to continuously push the boundaries of what is possible in healthcare, ensuring that we bring life-changing treatments to those who need them most. What You Will Achieve The purpose of the Senior Associate Scientist position is to provide the planning and execution of experiments designed to aid in defining manufacturing processes for biopharmaceuticals. The successful candidate will have a working knowledge of biochemistry, and related analytical chemistries, chromatography, centrifugation, precipitation, and filtration design principles. This position requires the design and execution of experiments using these technologies and the ability to evaluate and clearly reporting the results to laboratory colleagues and other affected functional areas. How You Will Achieve It Developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials. Will work with fellow scientists to develop robust, efficient, and scalable strategies to improve process performance. Conducting small-scale studies as well as pilot plant and manufacturing downstream purification studies. Based on study analyses, the role will develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes. Support process validation, quality by design, regulatory approaches, and quality systems. Prepare internally reviewed technical reports, deliver oral presentations to scientists and management, and publish externally. Executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes. Endorse and support changes to business infrastructure to ensure pipeline, legacy, and technology success.

Requirements

• Must-Have BS with 3+ years' experience or MS degree in a biological or engineering discipline (Biotechnology, Biochemistry, Chemical/Biochemical Engineering, or equivalent) with 0+ years of experience.
• 0-2 years' experience in recombinant protein/biomolecule purification process development, technology transfer and/or bioprocess manufacturing required.
• Demonstrated ability to drive for results and generate innovative research programs independently.
• Diverse work experience recovering recombinant proteins/biomolecules from mammalian and microbial/yeast cultures.
• Experience transferring Biotherapeutic processes to pilot plants or manufacturing organizations, and knowledge of data acquisition and controls systems in these environments is desirable.

Nice To Haves

• Applicants should be bright, organized, self-motivated, and capable of working independently, and in a collaborative environment.
• The successful candidate will possess strong oral and written communication skills.

Responsibilities

• Developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials.
• Will work with fellow scientists to develop robust, efficient, and scalable strategies to improve process performance.
• Conducting small-scale studies as well as pilot plant and manufacturing downstream purification studies.
• Based on study analyses, the role will develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes.
• Support process validation, quality by design, regulatory approaches, and quality systems.
• Prepare internally reviewed technical reports, deliver oral presentations to scientists and management, and publish externally.
• Executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes.
• Endorse and support changes to business infrastructure to ensure pipeline, legacy, and technology success.

Benefits

• In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary.
• We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments.
• Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level