Senior Associate Scientist

Regeneron Pharmaceuticals • Tarrytown, GA

1d • Onsite

About The Position

We are currently looking for a motivated Scientist to join the High Throughput Antibody Screening and Biomolecular Interaction Group within the Therapeutic Proteins team. As a Sr Associate Scientist, a typical day may include: Supporting Therapeutics Protein activities by implementing methods to characterize protein interaction kinetics and biochemical properties using SPR, BLI, ITC, and other analytical technologies in support of the company’s VelocImmune fully-human antibody pipeline. Essential duties and responsibilities may include, but are not limited to, the following: Antibody characterization, method development, and analytical support for biologics development using biochemical and biophysical methods. Troubleshooting established test methods used in development and release testing of screening reagents. Tabulate results and write summary reports of assay development. Present findings at group and interdepartmental meetings. Maintain lab supplies and equipment. Produce and maintain accurate records. You might be a good fit if you have the following: Kinetics analysis Protein chemistry Electrophoretic methods of analyses of proteins (SDS-PAGE, Western Blot) HPLC & FPLC techniques Immunoassays development (ELISA) Chromatography Spectroscopy Iso-Thermal Calorimetry Interpersonal, oral, and written communication skills Word processing, spreadsheet, and database management To be considered for this role, you must have the following: BS with 6+ yrs or a MS degree with 3+ yrs proven experience. Solid understanding in one or more of the following areas are needed: structural biology, biophysics, or chemical biology. The candidate is expected to have the ability to follow verbal and written instructions, be self-motivated, resourceful, and proactive, in addition to possessing excellent organizational, interpersonal, and problem solving skills. Knowledge and experience in using biophysical methodologies such as Biacore, Octet, or ITC to study protein/small molecule or protein/protein interactions and binding kinetics preferred. Good hands-on experience in protein chemistry such as (HPLC, FLPC, ion-exchange, affinity, size exclusion chromatography, and protein conjugation chemistry) or protein analysis (SDS-PAGE, Western-blot, ELISA). Highly motivated and able to work productively in a fast-paced team environment. Excellent communication skills required. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries’ specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $80,300.00 - $131,100.00 Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.

Requirements

• BS with 6+ yrs or a MS degree with 3+ yrs proven experience.
• Solid understanding in one or more of the following areas are needed: structural biology, biophysics, or chemical biology.
• The candidate is expected to have the ability to follow verbal and written instructions, be self-motivated, resourceful, and proactive, in addition to possessing excellent organizational, interpersonal, and problem solving skills.
• Excellent communication skills required.

Nice To Haves

• Kinetics analysis
• Protein chemistry
• Electrophoretic methods of analyses of proteins (SDS-PAGE, Western Blot)
• HPLC & FPLC techniques
• Immunoassays development (ELISA)
• Chromatography
• Spectroscopy
• Iso-Thermal Calorimetry
• Interpersonal, oral, and written communication skills
• Word processing, spreadsheet, and database management
• Knowledge and experience in using biophysical methodologies such as Biacore, Octet, or ITC to study protein/small molecule or protein/protein interactions and binding kinetics preferred.
• Good hands-on experience in protein chemistry such as (HPLC, FLPC, ion-exchange, affinity, size exclusion chromatography, and protein conjugation chemistry) or protein analysis (SDS-PAGE, Western-blot, ELISA).
• Highly motivated and able to work productively in a fast-paced team environment.

Responsibilities

• Antibody characterization, method development, and analytical support for biologics development using biochemical and biophysical methods.
• Troubleshooting established test methods used in development and release testing of screening reagents.
• Tabulate results and write summary reports of assay development.
• Present findings at group and interdepartmental meetings.
• Maintain lab supplies and equipment.
• Produce and maintain accurate records.

Benefits

• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level