Senior Associate Scientist, Analytical Operations

Gilead Sciences • Foster City, CA

2d • $115,260 - $164,120

About The Position

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come.  As a Senior Associate Scientist, Analytical Operations , at Gilead you will ... Perform Analytical Method Development & Testing Perform Liquid Chromatography (LC), Capillary Electrophoresis (CE), and ELISA-based assays to evaluate the impact of process parameters on product quality. Support method development, optimization, and validation for late-stage biotherapeutics in compliance with regulatory guidelines. Participate in process development, characterization, and comparability studies and analyze in-process and product-related impurities. The successful candidate will possess an understanding of analytical tools for therapeutic biologics process and product characterization as well as design and execute experiments to automate analytical tools to boost workflow efficiency. The candidate must be highly motivated to contribute to the research and development of biologics targeting unmet medical needs through biochemical characterization and novel method development supporting clinical and commercial programs. Experience in several of the following fields is strongly desired: analytical chemistry, biochemistry, high performance or ultra-performance liquid chromatography, electrophoretic separations, ELISA-based methods, automation (such as Hamilton and Tecan), and bioinformatics. Automation & Workflow Optimization Independently design and execute automation strategies to improve end-to-end testing efficiency, including data management tools. Operate, maintain, and troubleshoot automated liquid handling systems ( Hamilton and Tecan ) and other laboratory automation platforms. Lead technology development projects to implement innovative solutions and gain competitive advantages over standard industry practices. Collaboration & Scientific Leadership Work closely with cross-functional teams to advance analytical technologies and automation workflows. Provide input on experimental planning and execution, considering economic, regulatory, and safety factors. Present results, interpret data, and draw scientifically sound conclusions. Documentation & Compliance Author and revise analytical methods, protocols, and reports in accordance with GMP/GxP standards. Review testing data for accuracy and compliance with established protocols and specifications. Continuous Learning & Representation Stay current with scientific literature and novel technologies and apply knowledge to ongoing projects. Represent Gilead at national and international conferences, sharing insights and advancements in biologics analytical development.

Requirements

• At a future date, this position will relocate from Oceanside CA to the Gilead corporate HQ in Foster City, CA or will be hired directly to Foster City CA.
• Bachelor’s degree in a relevant scientific discipline (e.g., bioengineering, chemical engineering, biochemical engineering) with 5+ years of experience OR Master’s degree with 3+ years of experience in biologics analytical development.
• Hands-on experience with LC, CE, ELISA-based methods , and laboratory automation workflows.
• Proficiency in operating and troubleshooting Hamilton and Tecan systems.
• Knowledge of ICH guidelines , GMP/GxP practices is highly preferred.
• Strong problem-solving skills and ability to proactively identify and implement solutions.
• Excellent organizational and communication skills.
• Ability to work independently and collaboratively in a multidisciplinary environment.

Responsibilities

• Perform Analytical Method Development & Testing
• Perform Liquid Chromatography (LC), Capillary Electrophoresis (CE), and ELISA-based assays to evaluate the impact of process parameters on product quality.
• Support method development, optimization, and validation for late-stage biotherapeutics in compliance with regulatory guidelines.
• Participate in process development, characterization, and comparability studies and analyze in-process and product-related impurities.
• Independently design and execute automation strategies to improve end-to-end testing efficiency, including data management tools.
• Operate, maintain, and troubleshoot automated liquid handling systems ( Hamilton and Tecan ) and other laboratory automation platforms.
• Lead technology development projects to implement innovative solutions and gain competitive advantages over standard industry practices.
• Work closely with cross-functional teams to advance analytical technologies and automation workflows.
• Provide input on experimental planning and execution, considering economic, regulatory, and safety factors.
• Present results, interpret data, and draw scientifically sound conclusions.
• Author and revise analytical methods, protocols, and reports in accordance with GMP/GxP standards.
• Review testing data for accuracy and compliance with established protocols and specifications.
• Stay current with scientific literature and novel technologies and apply knowledge to ongoing projects.
• Represent Gilead at national and international conferences, sharing insights and advancements in biologics analytical development.

Benefits

• This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package.
• Benefits include company-sponsored medical, dental, vision, and life insurance plans.
• For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing
• Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees