Co-op: Screening & On-target NG
About The Position
Prime Medicine is seeking a highly motivated co-op to join the Screening & NGS team supporting Prime Editing programs. This role will contribute to high-throughput genome editing experiments in mammalian systems and sequencing-based evaluation of editing outcomes. The candidate will work at the interface of cell biology, genome editing, next-generation sequencing (NGS), and lab automation. In addition to supporting active screening efforts, the co-op will lead a defined project to optimize and automate components of the screening workflow to improve throughput, reproducibility, and data quality. This position offers hands-on experience with cutting-edge gene editing technologies in a fast-paced, collaborative R&D environment focused on developing transformative genetic medicines. We seek a driven team member passionate about advancing human health.
Requirements
- Pursuing a B.S. or M.S. in Molecular Biology, Genetics, Bioengineering, or related field
- Hands-on experience with core molecular biology techniques, including PCR and DNA extraction
- Experience with aseptic technique
- Familiarity with genome editing concepts
- Exposure to NGS workflows or sequencing-based assays
- Strong attention to detail, troubleshooting ability, and collaborative mindset
Nice To Haves
- Prior mammalian cell culture experience strongly preferred
- Hands-on experience with gene editing and/or NGS techniques
- Experience with laboratory automation and/or data analysis
Responsibilities
- Maintain and manipulate mammalian cell cultures using aseptic technique
- Perform cell transfections and execute gene editing experiments
- Isolate genomic DNA, prepare NGS libraries, and operate Illumina sequencing platforms
- Support development of automated liquid handling workflows
- Analyze and interpret sequencing data to assess editing efficiency and screening performance
- Maintain accurate experimental documentation using an electronic lab notebook system
Benefits
- Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.
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What This Job Offers
Career Level
Intern
