Scientist
About The Position
ABOUT STRM.BIO STRM.BIO (pronounced “storm bio”) is a VC-backed biotech startup building a new kind of gene therapy delivery platform based on naturally occurring extracellular vesicles (EVs). We're leveraging the unique biology of EVs to unlock targeted, scalable, and low-immunogenicity genetic medicines that target the bone marrow. We’re a small, fast-moving team based at The Engine in Cambridge, MA. We believe in simplicity, integrity, and keeping people at the center of everything we do. We’re here to do great science and build a company we’re proud of. THE OPPORTUNITY We’re looking for Scientists to help lead and grow our research engine. You’ll work shoulder-to-shoulder with technical leadership and a team of fellow Scientists to drive key programs forward and manage external collaborations. This is a hands-on, highly cross-functional role ideal for someone who’s ready to dive in and execute in equal measure. This is a full-time, on-site role.
Requirements
- Ph.D. in molecular biology, hematology, immunology, bioengineering, or related field; strong background in genetic engineering/gene therapy (primary cells/hematopoietic lineages a plus)
- Experience in in vitro, ex vivo, and in vivo studies assessing gene delivery, editing, and expression
- Solid working knowledge of genome editing tools (CRISPR, TALEN, ZFNs) and therapeutic editing in preclinical models
- Strong bench skills in molecular/cell biology (qPCR, RT-PCR, Western, microscopy, multiplex flow cytometry)
- Experience designing/handling DNA & mRNA molecules; exposure to construct design and NGS workflows preferred
- Experience with non-viral delivery systems (viral vectors, LNPs, EVs) and associated analytics
- In vivo experience including vivarium work and animal model handling
- Familiarity with electronic lab notebooks (ELNs) preferred
- Experience collaborating with CROs/external partners; CMC familiarity a plus
- Excellent communicator, highly organized, detail-oriented, collaborative
- Proficient in Microsoft Office (Excel, PowerPoint) for data analysis/presentation
Nice To Haves
- experience with startup ops, grant writing, or early product development
Responsibilities
- Support the Director of Research, Sr. Director of Platform Development, and R&D team in managing, coordinating, and supporting the research efforts across multiple collaborative research programs
- Contribute to, and lead as required, R&D efforts to meet project milestones, maintaining the standards of scientific rigor and adhering to ethical standards
- Maintain standards consistent with company culture and values
- Work closely with team members (internal and external) to maintain project development, implementation and troubleshooting of experiments, and ensure deliverables for both internal research projects and external scientific partnerships
- Generate, analyze, interpret, and share experimental results and ensure that all protocols, reagents, data, and analyses are documented following data integrity principles and prepared and made available in a timely manner
- Attend and present at team meetings to share results, and plan projects and experiments, with a keen eye for achieving company milestones
- Maintain comprehensive and up-to-date knowledge of extracellular vesicle biology, extracellular vesicles as therapeutics, and novel genetic engineering approaches
- Perform other duties as assigned, including all those associated with facilitating the smooth operation of a wet lab environment
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
