Spark Therapeutics-posted about 1 year ago
$112,600 - $169,000/Yr
Full-time • Entry Level
Philadelphia, PA
Ambulatory Health Care Services

The Scientist/Sr. Scientist position at Spark Therapeutics involves supporting early and late-stage drug product development activities within the process and technology development organization. The role focuses on formulation, process development, and analytical characterization of gene therapy products, contributing to the advancement of innovative healthcare solutions.

  • Design and analyze experiments related to drug product development.
  • Write and review protocols, reports, and tech transfer documents.
  • Prepare and present data and findings as needed.
  • Execute laboratory experiments as described in primary duties.
  • Manage the design and execution of analytical biophysical characterization and high throughput formulation development.
  • Ph.D. in biochemistry, pharmaceutics, chemical engineering, material sciences, mechanical engineering, or related discipline with 0-2 years of industry experience, or MS with 4-6 years of experience, or BS with 6-8 years of experience.
  • Experience in large molecule drug product development, material sciences, and/or container closures and devices development is preferred.
  • Strong background in gene therapies, vaccines, cell therapies, and/or biological molecules is strongly preferred.
  • Experience with rAAV and sterile parenteral products is a plus.
  • Understanding of Freeze Drying/Lyophilization of biologics is a plus.
  • Good scientific publication record and/or patent filing is a plus.
  • Experience with high throughput formulation development and analytics is a plus.
  • Background knowledge of large scale GMP manufacturing and GXP compliant documentation is a plus.
  • Competitive salary range from $112,600 to $169,000 based on education and experience.
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