Scientist/Senior Scientist

ZoetisLincoln, NE
1d

About The Position

Zoetis Veterinary Medicine Research and Development (VMRD) is seeking an enthusiastic colleague for a challenging and fast-paced position in Biologics Product Development in Lincoln, Nebraska. The incumbent is responsible for the design and execution of vaccine formulation and delivery strategies for different antigen types (peptide, protein, nucleotides, viral, bacterial etc.). The scientist in this position is also responsible for working collaboratively with multi-disciplinary teams, author technical documents, leading / supporting organizational initiatives, assessing new capabilities / technologies. The selected individual is expected to have knowledge of immune pathways, molecular biology, and formulation approaches used for vaccine products. Colleague would be responsible for leading a team of vaccine formulation scientists.

Requirements

  • M.S. with 5+ years of relevant experience, OR Ph.D. with 3+ years of experience in academia, biotechnology, or the pharmaceutical industry
  • Degree in Immunology, Pharmaceutical Sciences, Biomedical Engineering, Drug Product Development, or a related field
  • Research focus on adjuvant research, formulation, and delivery aspects of vaccines or immunotherapeutics

Nice To Haves

  • Experience with various types of vaccine antigens and adjuvant systems
  • Advanced knowledge of drug delivery systems for biologicals
  • Hands on experience with emulsion formulation development
  • Experience in development of mRNA-based vaccines
  • Experience in parenteral formulation development for biologics and lyophilization techniques
  • Understanding of biochemistry, degradation pathways, and general approaches for antigen and protein stabilization
  • Experience with biophysical techniques and ability to apply them for characterization and problem-solving during vaccine formulation development
  • Ability to independently contribute from the bench
  • Strong verbal and written communication skills

Responsibilities

  • Design vaccine delivery approaches to attain desired immune response, based on biology of disease and intervention approaches
  • Design and conduct studies to characterize molecular and biophysical properties of various types of antigens (peptides, proteins, nucleotides, viral, bacterial etc.)
  • Design and development of parenteral biologic formulations (solutions, emulsions, lyophilized products, and other dosage forms)
  • Develop and optimize lyophilization-cycle
  • Develop and prepare vaccines for clinical studies
  • Work with cross-functional, co-dev and project teams (internal and external) to execute plans and deliverables
  • Keep abreast of relevant new technologies & regulatory expectations/requirements
  • Ensure work activities are aligned with relevant Quality and EHS requirements
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