Scientist/Scientist II, Translational Medicine
About The Position
About Jade Biosciences Jade Biosciences is focused on developing innovative, best-in-class therapies to address critical unmet needs in autoimmune diseases. Our lead candidate, JADE101, is designed to inhibit the cytokine APRIL (A Proliferation-Inducing Ligand) and is being developed for the treatment of immunoglobulin A nephropathy ( IgAN ), a chronic kidney disease that can impair kidney function over time. JADE101 aims to reduce harmful IgA antibodies, lower proteinuria (a key marker of kidney damage), and preserve long-term kidney function. A Phase 1 healthy-volunteer study of JADE101 is ongoing, with interim, biomarker-rich data expected in the first half of 2026. Jade’s pipeline also includes a second development candidate, JADE201, and an undisclosed antibody discovery program, JADE-003, both currently in preclinical development. For more information, visit JadeBiosciences.com and follow us on LinkedIn . Role Overview The Research & Translational Medicine group at Jade is looking to add a Scientist /Scientist II to our team. The Scientist , Translational Medicine will develop , validate , and implement bioanalytical and biomarker assays to support Jade’s preclinical and clinical programs . . Th is is an exciting opportunity to join a growing team, develop your skills and experience, and develop great professional relationships in a fast-paced environment. This is a fully remote role and will require occasional travel.
Requirements
- Scientist level: Ph.D. in a relevant scientific discipline with 0-3+ years of experience, M.S. with 8+ years, or B.S. with 10+ years in bioanalytical or biomarker assay development.
- Scientist II level: Ph.D. in a relevant scientific discipline with 3-5+ years of experience, M.S. with 10+ years, or B.S. with 12+ years in bioanalytical or biomarker assay development.
- Proven experience managing sample analysis for global clinical trials and interfacing with regulatory authorities.
- Demonstrated ability to manage CROs, including contracting, study design, and technical oversight.
- Strong laboratory and project management skills, with expertise in critical thinking and scientific problem-solving.
- Hands-on experience with diverse assay platforms (e.g., flow cytometry, immunohistochemistry, ELISA, Luminex, MSD).
- Solid understanding of drug development processes and regulatory requirements.
- Excellent analytical, written, and oral communication skills, with strong interpersonal abilities.
- Highly motivated, detail-oriented, and curious, with a creative approach to scientific challenges.
- Ability to travel for company meetings and scientific conferences as needed.
Responsibilities
- Design, develop, and optimize bioanalytical and biomarker assays to assess drug potency, mechanism of action, and functional activity across preclinical and clinical programs.
- Select, qualify, and manage CRO partners for bioassay and biomarker development, transfer, and analysis, ensuring seamless execution, alignment on timelines, budgets, and quality expectations.
- Conduct detailed review and analysis of bioanalytical and biomarker data, ensuring rigorous scientific validity and compliance with regulatory standards.
- Collaborate with clinical and regulatory teams to draft, review, and finalize bioanalytical and biomarker sections of clinical protocols, investigator brochures, and regulatory submissions (e.g., IND, BLA), ensuring scientific accuracy and compliance with applicable guidelines.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
Number of Employees
11-50 employees
