Scientist, Purification Process

Thermo Fisher ScientificWilmington, DE
3dOnsite

About The Position

Join us as a Scientist! This is a fully onsite role based at our customer’s site in Wilmington, DE. We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate. Must be legally authorized to work in the United States without sponsorship. Must be able to pass a comprehensive background check, which includes a drug screening. Scientist, Purification Process Science Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner. At PPD, part of Thermo Fisher Scientific, we hire the best, develop ourselves and each other, and recognize the power of being one team. It's not just talk; our award-winning training programs speak for themselves. Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to demonstrate the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits. Location/Division Specific Information Onsite in Wilmington, DE Our client is seeking a motivated and dedicated protein purification scientist to support protein purification process development and optimization primarily for novel therapeutic monoclonal antibody products including bispecifics throughout all stages of clinical trials.

Requirements

  • BS degree in biochemistry, bioengineering, biology, chemistry or related fields, preferably with some relevant industry experiences with 2-4 years of experience or MS in above fields with 1-2 years of experience. In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
  • Good knowledge in protein chemistry and bioprocessing
  • Good knowledge and hands-on experiences in various types of column/membrane chromatography (affinity, size exclusion, ion exchanges, multi-mode) and filtration technology; TFF
  • Experiences in using AKTA line of purification instruments
  • Experiences in using ultrafiltration/diafiltration instrument for buffer exchange, product concentration, and formulation
  • Experiences in protein analysis such as HPLC, CGE, ELISA, etc. is a plus
  • Aseptic Technique
  • Good verbal and written communication skills, organized, cooperative, independent, meticulous

Nice To Haves

  • Experiences in high-throughput protein purification platform are desirable but not required.

Responsibilities

  • Conduct routine protein purification to support formulation team’s material needs and cell culture development
  • Conduct high-throughput protein purification to support cell line development
  • Provide assistance in purification process development, optimization, and scale-up manufacturing
  • Conduct routine analyses of in-process samples using relevant product purity and process impurity analytical tools
  • Prepare buffers and solutions needed for laboratory work
  • Present work summary in the group meeting
  • Write routine electronic laboratory notebook
  • Other responsibilities as assigned
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