Scientist, Oncology (Histology and Immunohistochemistry)

Regeneron Pharmaceuticals • Tarrytown, GA

2d • Onsite

About The Position

The Histology team is seeking a highly motivated Senior Associate Scientist/Scientist to join the Oncology/Immuno-Oncology department at Regeneron Pharmaceuticals, as we make transformational advances in harnessing the power of the immune system to fight cancer. The position will involve executing complex histological studies to reveal potential target expression and investigate the mechanism of action of novel immuno-oncology therapeutics. This role will be deeply involved in the development of cutting-edge therapeutics including bispecific antibodies, antibody-drug conjugates, and CAR-T cells. You will work closely with other team members and collaborators to advance programs spanning from initial target discovery to support of ongoing clinical-stage therapeutics. As a Senior Associate Scientist/Scientist, a typical day may include the following: Independent execution of immunohistochemistry (IHC) assays, including the use of high-throughput Ventana and Biocare autostainer platforms RNA in-situ hybridization (ISH) based assays using modern platforms such as RNAscope. Histological tissue processing, microtomy, cryosectioning, and H&E staining of human and non-human tissues Development and characterization of novel antibodies and probes for IHC and ISH assays Scanning of slides and assembly of images in PowerPoint and other formats for presentation Basic analysis of images and frequent collaboration with members of the Pathology department This role may be for you if: You have proven basic histology skills and a desire to further expand and develop your skill set and knowledge of the immuno-oncology drug development process. You are enthusiastic to learn new skill sets, including multiplex IHC, complex image analysis, and performing cell culture You are detail-oriented, have strong time management skills, and appreciate an opportunity for growth as a scientist. You possess the drive and desire to learn how to troubleshoot and think outside the box to solve complex problems. You have excellent written and verbal communication skills, and the ability to work as part of a diverse team.

Requirements

• A BS with 7 years or MS with + 5+ years of laboratory experience (in academia or industry) in a relevant scientific discipline (Immunology, Oncology, Molecular/Cell Biology) and direct hands-on experience executing histology and immunohistochemistry techniques.
• You have proven basic histology skills and a desire to further expand and develop your skill set and knowledge of the immuno-oncology drug development process.
• You are enthusiastic to learn new skill sets, including multiplex IHC, complex image analysis, and performing cell culture
• You are detail-oriented, have strong time management skills, and appreciate an opportunity for growth as a scientist.
• You possess the drive and desire to learn how to troubleshoot and think outside the box to solve complex problems.
• You have excellent written and verbal communication skills, and the ability to work as part of a diverse team.

Nice To Haves

• Experience with autostainer platforms (e.g., Ventana or Biocare) is a plus.
• Experience in the research and development of targeted cancer therapeutics, including antibodies and CAR-T cells, is an advantage.
• The ideal candidate will possess strong organizational skills including the ability to manage and record details of several complex projects simultaneously.
• A demonstrated ability to communicate seamlessly and work across diverse groups to achieve a common goal is also desired.

Responsibilities

• Independent execution of immunohistochemistry (IHC) assays, including the use of high-throughput Ventana and Biocare autostainer platforms
• RNA in-situ hybridization (ISH) based assays using modern platforms such as RNAscope
• Histological tissue processing, microtomy, cryosectioning, and H&E staining of human and non-human tissues
• Development and characterization of novel antibodies and probes for IHC and ISH assays
• Scanning of slides and assembly of images in PowerPoint and other formats for presentation
• Basic analysis of images and frequent collaboration with members of the Pathology department

Benefits

• comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels!

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees