ScientistNew

Bridgebio Pharma • San Carlos, CA

324d • $120,000 - $150,000

About The Position

ML Bio Solutions (ML Bio), a BridgeBio company, is a biotechnology company founded in 2018, yet the company's founders have been dedicated to finding a cure for Limb girdle muscular dystrophy type 2I/R9 FKRP-related (LGMD2I/LGMDR9) for close to twenty years. ML Bio is developing BBP-418, potentially the first oral treatment for patients with LGMD2I. BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas, including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs. Our focus on scientific excellence and rapid execution aim to translate today's discoveries into tomorrow's medicines. We have U.S. offices in San Francisco, Palo Alto, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zurich, Switzerland, and are expanding across Europe.

Requirements

• Minimum Education requirement: PhD or MS degree in Biology or related field with 3-5 years of Industry experience
• Minimum 2 years GLP experience
• Prior experience with CRO management
• Assay development experience
• Must be proficient in Western Blot assays
• Strong hands-on proficiency in other wet lab skills such as ELISA, plate-based assays, and other biophysical protein characterization methodologies
• An understanding of all stages of drug development
• Data collection, analysis, and data interpretation skills, proficient in Microsoft Office Suite
• Demonstrated strong analytical and strategic thinking skills
• Strong attention to detail and highly organized
• Excellent written, oral communication and presentation skills
• Strong interpersonal skills and can-do attitude with flexibility and ability to adapt
• Critical thinker who is proactive with a highly collaborative style and team-focused approach

Responsibilities

• Strong hands-on wet lab skills such as Western Blotting, ELISA, plate-based assays and other biophysical protein characterization methodologies
• Process/analyze assay results and produce technical reports and contribute to NDA modules for ongoing clinical trials
• Under the supervision of the senior scientist, support the tracking of the sample analysis of the primary biomarker as well as ensure that all CRO activities are aligned with study timelines, budgets, and quality standards
• Ensure compliance with regulatory requirements for biomarker assays
• Work with biostatistics and data management teams to integrate biomarker data into clinical development plans
• Collaborate with drug discovery, clinical development, and regulatory affairs teams to integrate biomarker strategies
• Support internal initiatives to develop best practices, lessons learned, problem-solving, and risk mitigation
• Adhere to company standards, and compliance in current industry standards and practices
• Adhere to safety regulations for handling and disposing of human biomaterials and reagents
• Proper maintenance of laboratory notebooks and forms in accordance with company policies and practices. Routine maintenance, and upkeep of laboratory

Benefits

• Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
• A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
• An unyielding commitment to always putting patients first
• A de-centralized model that enables our program teams to focus on advancing science and helping patients
• A place where you own the vision - both for your program and your own career path
• A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
• Access to learning and development resources to help you get in the best professional shape of your life
• Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
• Flexible PTO
• Rapid career advancement for strong performers
• Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time
• Partnerships with leading institutions
• Commitment to Diversity, Equity & Inclusion

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Professional, Scientific, and Technical Services
• Education Level: Ph.D. or professional degree