Scientist, Molecular Biology

Legend Biotech • Philadelphia, PA

195d • $93,463 - $128,512

About The Position

Legend Biotech is seeking a Scientist, Molecular Biology as part of the Vector Biology team based in Philadelphia, PA. This role designs and develops lentiviral vectors and plasmids, manages the plasmid database, and generates engineered cell lines to support CAR-T assays. It involves small-scale LVV production, functional characterization, and close collaboration with cross-functional teams.

Requirements

• BS degree with 5+ years; MS degree with 3+ years; or PhD degree with no prior experience in biochemistry, virology, molecular biology, or related field.
• Champion in molecular biology including cloning, Western blotting, and gene editing
• Able to adjust workload based upon priorities
• Strong knowledge & experience in molecular/cellular biology
• Ability to think strategically, balance short-term goals and maintain flexibility is preferred.
• Experience in single cell cloning and high throughput screening is a plus.

Responsibilities

• Design lentiviral vector and helper plasmids for existing and future programs
• Cloning and plasmid construction internally and/or outsourcing
• Manage plasmid database and become a lead liaison for plasmid/LVV designs
• Generate cell lines such as KO or overexpression for CAR-T cell assays
• Small scale LVV production using suspension cell lines
• Conduct molecular and cellular assay for all aspects of LVV function & characterization
• Work independently in planning, performing, analyzing, reporting and presenting experimental data
• Closely working with upstream, downstream and analytical team.

Benefits

• Medical, dental, and vision insurance
• 401(k)-retirement plan with company match that vests fully on day one
• Equity and stock options available to employees in eligible roles
• Eight weeks of paid parental leave after just three months of employment
• Paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays
• Flexible spending and health savings accounts
• Life and AD&D insurance
• Short- and long-term disability coverage
• Legal assistance
• Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance
• Commuter benefits
• Family planning and care resources
• Well-being initiatives
• Peer-to-peer recognition programs

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Professional, Scientific, and Technical Services
• Education Level: Bachelor's degree