Scientist, Medicinal Chemistry

Neurocrine Biosciences Inc. • San Diego, CA

67d • $88,000 - $127,550

About The Position

Responsible for the design, synthesis, purification, and characterization of intermediates and bioactive compounds through the use of techniques such as column chromatography (e.g., high performance liquid chromatography, automated normal phase purification), nuclear magnetic resonance and parallel or combinatorial synthesis. Prepares technical reports, summaries, protocols, and quantitative analyses. Responsible for the communication and presentation of results to the project team in order to facilitate effective decision making.

Requirements

• BS/BA degree AND 2+ years of relevant experience, including familiarity utilizing any or all of the following: parallel synthesis, lab automation, and purification in the optimization of lead compounds is preferred OR
• MS/MA degree in Synthetic Organic Chemistry preferred AND some similar experience noted above OR
• PhD in Synthetic Organic Chemistry or related field preferred AND some related postdoctoral experience preferred
• Working knowledge of any or all of the following: organic synthesis, parallel synthesis, medicinal chemistry, lab automation, and purification in the optimization of lead compounds is preferred
• Recognizes fundamental anomalies in data points and identifies issues in experiments / processes
• Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
• Strong knowledge of scientific discipline
• Good knowledge of scientific principles, methods and techniques
• Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
• Strong computer skills
• Good problem-solving, analytical thinking skills
• Detail oriented
• Ability to meet deadlines
• Excellent communication skills with the ability to collaborate with cross-functional scientists

Responsibilities

• Plays key role in the rapid optimization of lead molecules utilizing modern technology available to medicinal chemists such as automated synthesis and purification
• Participates in a multidisciplinary team committed to the continuous improvement of the lead optimization process as well as the expeditious identification of development compounds
• Designs, plans and conducts synthesis of intermediates and analog libraries as well communicates results to the project or program team
• Other duties as assigned

Benefits

• retirement savings plan (with company match)
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Chemical Manufacturing
• Number of Employees: 1,001-5,000 employees