Scientist, Immunology Cell Therapy Discovery

AstraZeneca • Waltham, MA

41d

About The Position

AstraZeneca, a global leader in biopharmaceuticals, is committed to discovering and delivering innovative therapies that transform patient outcomes. We are seeking a dedicated and hands-on Scientist to join our Immunology Cell Therapy Discovery team. This role focuses on active laboratory involvement and collaboration to advance cell therapy discovery projects. The ideal candidate will demonstrate strong teamwork skills, a willingness to learn, and a humble attitude. At AstraZeneca, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. With one of the broadest and deepest Immunology pipelines in the industry, there are many opportunities to work with new and novel drugs. Our collaborative environment empowers us to take smart risks, challenge the norm, and learn from failures. We are united in our vision to eliminate cancer as a cause of death, making bold moves that truly improve patient outcomes. Join us in our mission to make a meaningful difference for patients around the world!

Requirements

• Bachelor's degree with 3+ years of experience in a relevant scientific field or significant relevant experience and knowledge of Cellular Therapy, Immunology, and Immune-mediated Diseases from working in the life science sector.
• In vivo skillset including animal handling, mouse tumor models, standard routes of dosing and engraftment
• Experience in developing cellular therapies including CAR-T, TCR-T, and/ or TIL therapies
• Proficiency in transfection/transduction, expansion, and cell culture of primary human /mouse T cells and cell lines
• Hands-on expertise in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, cytokine measurement
• Proficiency with multi-parameter flow cytometry (Immunostaining, acquisition, and analysis)

Nice To Haves

• Background in drug discovery and development in the pharmaceutical industry
• Advanced degree in related field

Responsibilities

• Conducts hands-on drug discovery research experiments
• Works collaboratively in a matrix and fast-paced environment
• Assesses and reports data with a clear understanding of its implications within the overall context of drug discovery
• Maintains a proven understanding of approaches to drug discovery and applies a broader functional knowledge of the procedures used by diverse project groups to support the department where needed
• Provides technical instruction to the team and allocates administrative work where possible
• Ensures own work, and work of peers, is compliant with relevant internal AstraZeneca standards and external regulations

Benefits

• Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles.
• Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees