Scientist III- LC/MS

BioAgilytix • Durham, NC

184d

About The Position

At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly. You’ll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients who need them. Our Liquid Chromatography/Mass Spectrometry (LC/MS) team is seeking a Scientist III to serve as Bioanalytical Project Manager (BPM)/Principal Investigator (PI), overseeing all aspects of bioanalytical studies—including project scope definition, proposal preparation, timelines, scheduling, budget, and revenue management. This role is ideal for someone with a strong background in method development, GxP-compliant validation, and targeted and untargeted analysis using chromatography and mass spectrometric platforms.

Requirements

• Bachelor’s degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than 12 years’ experience in a scientific laboratory environment; or
• Master’s degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than ten (10) years’ experience in a scientific laboratory environment; or
• PhD in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than eight (8) years’ experience in a scientific laboratory environment.
• Knowledge of regulatory guidance and industry best practices for LC/MS, and other large molecule assays.
• Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique.
• Advanced capabilities in data analysis, data visualization statistical analysis.
• Experience with Microsoft Word, Excel, Sciex OS/Analyst, MassLynx, XCalibur, Chromeleon, Watson LIMS, JMP, Graphpad Prism.
• Knowledge of GDP, GLP, GCLP, GCP.

Nice To Haves

• Experience with development, validation and execution of chromatographic and mass spectrometric assays (LC/MS), and/or ability to perform most tasks associated with custom research planning and bench work.
• Must work effectively within team to meet objectives under time constraints.
• A knack for designing efficient and impactful experiments.
• Experience working in a regulated environment, with a thorough understanding of GDP, GLP, GCLP, GCP.
• Independence, enthusiasm, openness, and adaptability.
• Demonstrated effective communication skills.
• The ability to inspire others to do their best work and drive results.
• Excellent customer service skills (internal and external).

Responsibilities

• Serve as Bioanalytical Project Manager (BPM)/Principal Investigator (PI), overseeing all aspects of bioanalytical studies including project scope definition, proposal preparation, timelines, scheduling, budget, and revenue management.
• Act as primary client contact, presenting data, ensuring clear communication, and aligning project deliverables with client timelines and expectations.
• Lead assay development, validation, and sample analysis of biologics, proteins, peptides, ADCs, and/or biomarkers using chromatographic and mass spectrometric (LC/MS) techniques in support of preclinical, clinical, and product release studies.
• Design, plan, and execute experiments independently; troubleshoot assays; analyze and interpret data; prepare summary tables, plans, reports, and SOPs.
• Ensure GLP compliance throughout assay development, validation, and sample analysis activities, including prompt identification and notification of deviations and preparation of associated documentation.
• Set up and manage studies in LIMS; maintain accurate laboratory records, worksheets, and raw data with peer review.
• Train, mentor, and direct junior scientists and analysts, including preparing and reviewing scientific training materials.
• Provide scientific leadership by planning experimental designs for junior staff and driving bioanalytical projects to successful completion.

Benefits

• Medical Insurance (HDHP with HSA; PPO)
• Dental Insurance
• Vision Insurance
• Flexible Spending Account (medical; dependent care)
• Short Term Disability | Long Term Disability
• Life Insurance
• Paid Time Off (4 weeks per year)
• Parental Leave
• Paid Holidays (9 scheduled; 5 floating)
• 401k with Employer Match
• Employee Referral Program

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree