Scientist II

WuXi AppTec•San Diego, CA

1d•$82,731 - $107,132

About The Position

PIPELINE OPENING HD Biosciences, Inc. (San Diego), a WuXi AppTec Company, is expanding its in vitro Pharmacology. We’re seeking highly skilled and motivated Scientist II to lead assay development projects and support target discovery and validation efforts for HTS and assay screening group. Responsibilities • Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required.• Normally receives minimal instructions on routine work and detailed instructions on new assignments.• Works under close supervision from supervisor or senior personnel.• Performs support functions (e.g. Runner function) in the (fill in Specific Dept.)• Ability to work in a team environment and independently as required• Maybe required to work Holidays and weekends• Maybe required to work Overtime ( Remove only for Exempt positions) • Contributes to the overall operations and to the achievement of departmental goals• Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures.• Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices• Other duties as assigned • May be required to assist in other departments Job Requirements: • Design, implement, and perform projects for functional assay development. • Proven hands-on experience with cell based assays and biochemical assays.• Support target discovery and validation efforts by independently developing and performing assays to evaluate biologic drug targets and candidates, such as GPCR, Ion-channels, Enzymatic assay, kinase assays, etc.• Develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats.• Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques.• Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred• Scientific creativity, critical thinking and fast learning capabilities.• Industrial drug R& D experience is a plus • Effectively communicate with internal team colleagues and external clients to promote a world-class services. Qualifications • 5-10 years of relevant experience or equivalent• Master or PhD degree preferred in Biochemistry, Biotechnology or Molecular Biology.• Demonstrated strong understanding of complex scientific procedures with technical proficiency in molecular and cell biology• Industry experience in Pharma/Biotech or close exposures to R&D process is preferred. Prior work in CRO in a commercial setting will be considered an additional strength.• Outstanding written and oral communication skills, and interpersonal skills to seamlessly fit within a teamwork driven environment.

Requirements

Proven hands-on experience with cell based assays and biochemical assays.
Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques.
Scientific creativity, critical thinking and fast learning capabilities.
5-10 years of relevant experience or equivalent
Master or PhD degree preferred in Biochemistry, Biotechnology or Molecular Biology.
Demonstrated strong understanding of complex scientific procedures with technical proficiency in molecular and cell biology
Outstanding written and oral communication skills, and interpersonal skills to seamlessly fit within a teamwork driven environment.
Proficient in Oral & Written communication skills
Need to be able to read, write and understand English (Mandarin)
Proficient in Microsoft (Excel, Word, Outlook)
Must be able to work in an office environment with minimal noise conditions.
Must be able to work in Lab setting with exposure to Animals/biohazards / Chemicals (List specific Chemicals)
Must not have animal allergies to applicable species in this facility
Must be able to wear appropriate PPE
Must be able to work in environment with variable noise levels
Ability to stand /Sit/walk for long periods of time
Ability to Lift 10 lbs routinely
Ability to crouch, bend, twist, and reach
Ability to push/pull 10 lbs routinely/ often / occasionally
Clarity of Vision
Ability to identify and distinguish colors
Must be able to perform activities with repetitive motions
Ability to climb Ladders / Stairs / Scaffolding
Ability to work in variable temperatures high to freezing
Inside/outside working conditions

Nice To Haves

Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred
Industrial drug R& D experience is a plus
Industry experience in Pharma/Biotech or close exposures to R&D process is preferred. Prior work in CRO in a commercial setting will be considered an additional strength.

Responsibilities

Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required.
Normally receives minimal instructions on routine work and detailed instructions on new assignments.
Works under close supervision from supervisor or senior personnel.
Performs support functions (e.g. Runner function) in the (fill in Specific Dept.)
Ability to work in a team environment and independently as required
Maybe required to work Holidays and weekends
Maybe required to work Overtime ( Remove only for Exempt positions)
Contributes to the overall operations and to the achievement of departmental goals
Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures.
Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices
Other duties as assigned
May be required to assist in other departments
Design, implement, and perform projects for functional assay development.
Support target discovery and validation efforts by independently developing and performing assays to evaluate biologic drug targets and candidates, such as GPCR, Ion-channels, Enzymatic assay, kinase assays, etc.
Develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats.
Effectively communicate with internal team colleagues and external clients to promote a world-class services.