About the position
In the Immuno-Oncology team, we are looking for an enthusiastic, inventive and team-oriented scientist to join us in the creation cutting-edge cellular treatments for cancer and other serious diseases. We are looking for colleagues with a strong background in one or multiple areas including: Immuno-Oncology, Oncology or Immunology, and who possess strong expertise in T-cell biology, intricate multicolor flow cytometry, and in vivo mouse models. The ideal candidate would have a remarkable scientific record, excellent communication and interpersonal abilities, be passionate about scientific research, and excel at pushing boundaries for innovation. We value candidates who are adept at problem-solving and approach difficulties with optimism. The chosen individual will join a dynamic, creative and goal-oriented atmosphere dedicated to making impactful advances in the way we treat disease.
Responsibilities
- Develop innovative adoptive cell therapies to treat cancer or other serious diseases.
- Design, execute, and analyze in vitro experiments (some examples include engineering of CAR T-cells, cytotox, ELISA, proliferation assays, flow cytometry analysis, cell culture).
- Design, execute and analyze in vivo preclinical studies (some examples of procedures include tumor implantation, adoptive cell therapy administration, mice dosing through different administration routes, tumor monitoring, blood collection and multiple tissue analysis).
- Efficiently and clearly present and communicate scientific data to the team, cross-functionally and at external meetings.
- Pro-actively suggest and evaluate innovative cell engineering solutions and develop new assays to enhance the company's intellectual portfolio and contribute to peer-reviewed publications.
- Stay up to date with external scientific research from academic and industry institutions.
- Keep timely detailed documentation of experiments.
- Effectively plan and manage projects and deliverables to meet deadlines.
- Foster cross-functional collaborations and train other colleagues.
- Prioritize company objectives and work towards shared success.
- Other duties as necessary to ensure the daily operations of the lab and support the team.
Requirements
- PhD in oncology, immunology, or equivalent (minimum of 3 years of experience after PhD in related role).
- Experience in human T-cell biology, immuno-oncology and knowledge in cell engineering technologies.
- Hands on experience and troubleshooting proficiency in immunology assays including immune cell isolation, multicolor flow cytometry, immune cell and cytokine profiling assays using conventional and next-generation analytical methods.
- Demonstrated experience designing and executing mouse tumor model experiments including mouse handling (injections- IV, SC, IP- and organ dissection).
- Excellent abilities to analyze and synthesize data for different audiences and report types while supporting decision-making processes.
- Proficiency in molecular biology as well as analyzing and manipulating DNA/protein sequences using bioinformatics software is desired.
- Basic knowledge of gene editing and next-generation sequencing technologies is a plus.
- Experience in working in matrixed environments and in project management is desired.
- Strong record of scientific publications and demonstrated scientific curiosity.
- Willingness to quickly adapt, innovate, discover new approaches, collaborate and support the team towards shared company goals.
- Candidates should be authorized to work in the U.S., preferably without the need for current, or future, sponsorship.
Nice-to-haves
- Proficiency in molecular biology as well as analyzing and manipulating DNA/protein sequences using bioinformatics software is desired.
- Basic knowledge of gene editing and next-generation sequencing technologies is a plus.
- Experience in working in matrixed environments and in project management is desired.
