Scientist II, Analytical Chemistry

Insmed Incorporated • San Diego, CA

3d • Onsite

About The Position

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: We’re looking for a Scientist II on the Analytical Development team to help us expand what’s possible for patients with serious diseases. Reporting to the Senior Scientist, Analytical Development, you’ll specialize in HPLC and LCMS-based analytical development for large molecules, with a focus on groundbreaking gene therapy products such as AAV vectors and other complex biologics.

Requirements

• You have a degree in analytical chemistry or related field with PhD and 1+ years post-graduate experience in method development, Master’s with 3+ years related experience, or Bachelor’s with 5+ years of related experience.
• Deep technical understanding of and hands-on experience with HPLC / LCMS and other protein biochemistry characterization methods including but not limited to spectroscopy, capillary electrophoresis (CE-SDS), SDS-PAGE, Western Blot, and ELISA techniques
• Expertise with Orbitrap (Thermo) and QQQ (Sciex) systems
• Proven track record in methods development, including experimental design, execution, and evaluation
• Excellent communication skills (verbal and written)
• Highly organized with a strong attention to detail, clarity, accuracy, and conciseness
• Strong analytical and problem-solving skills
• Ability to thrive in a dynamic work environment and show a commitment to diversity in individuals and ideas

Nice To Haves

• Experience in scripting or coding (e.g. Python or R)

Responsibilities

• Support QC and may also serve in supporting R&D for non-clinical/clinical biomarker using LCMS and Separations-related needs.
• Serve as a subject-matter-expert for all HPLC and LCMS based method development and testing.
• Write and review protocols, SOPs, reports and other product development documents
• Protein identification, quantification and characterization from the therapeutic evaluation of our compounds in preclinical development studies
• Participate in cross-disciplinary mentoring and training of entry-level and junior scientists
• Assist with coordination and day-to-day management of site operations
• Perform data review to ensure accuracy, completeness, and validity
• Summarize experimental data into technical reports and for external publications
• Present scientific results to R&D and Technical Development teams, and periodically at scientific conferences in poster or podium format
• Maintain proper documentation of experimental procedures and results via electronic laboratory notebook
• Maintain specific laboratory equipment
• Define and implement state-of-the art technology to support non-clinical and clinical biomarker and product quality characterization needs
• Conceptualize, construct, validate, and implement screening platforms to enable biomarker discovery and screening in tissue samples

Benefits

• Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
• Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
• 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
• Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
• Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree