Scientist I, Formulation Development

Elektrofi • Boston, MA

74d • Remote

About The Position

Elektrofi is seeking a motivated individual to join our biotech company as a Scientist I, Formulation Development to support the development of our novel Hypercon formulation platform. The individual will join a growing, multidisciplinary team of scientists/engineers and industry professionals.

Requirements

• PhD with 0+ years, Masters with 2+ or Bachelors with 4+ years experience in Pharmaceutical Sciences, Chemical Engineering, Biochemistry, Material Science, Bioengineering, Physical Chemistry, Pharmaceutical Engineering, or a related field.
• Demonstrated experience developing and optimizing protein formulations.
• Knowledge of protein biochemistry, protein stability and formulation design approaches to mitigate protein degradation mechanisms.
• Knowledge of rheology and flow characteristics of non-Newtonian fluids and relevant modeling.
• Understanding of statistical methods and design of experiments methodology.
• Familiarity with standard office software (MS Office, Teams, SharePoint, JMP) and electronic laboratory notebooks.
• Demonstrated good laboratory skills, organizational skills, and attention to detail.
• Ability to work in multi-disciplinary teams.

Nice To Haves

• Experience in high concentration protein formulation, long acting injectables, or lyophilized product development.
• Experience in primary container selection, including compatibility and container closure integrity evaluations.
• Experience in the development of pre-filled syringes and other combination products.

Responsibilities

• Coordinate and execute drug product development activities to formulate a wide range of therapeutic biologic modalities into our proprietary Hypercon suspension using QbD principles.
• Utilize scaled-down process models and stress conditions to select formulations that optimize drug product performance, including protein stability and suspension physical properties.
• Independently design and execute hypothesis-driven experiments to drive continuous improvement of development workflows and enhance product understanding.
• Manage, compile and analyze data using analytical software.
• Represent the formulation development function on cross-functional CMC project teams internally and externally to our biopharmaceutical partners.
• Manage relevant method protocols, present findings and author reports to support regulatory submissions (IND, IMPD, BLA, etc.) and technology transfer.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Professional, Scientific, and Technical Services
• Education Level: Ph.D. or professional degree
• Number of Employees: 51-100 employees