Scientist I (Contract), Drug Product Analytics
About The Position
Vaxcyte is looking for an energetic and talented individual to join our Drug Product Development team. The candidate must have knowledge of and practical experience in analyzing and characterizing biomolecules (proteins, polysaccharide conjugates, vaccines) using a variety of methods, especially immunoassays and multiplexed immunoassay formats. Experience in analyzing vaccine and adjuvant-containing formulations is a plus. In addition, Vaxcyte is looking for an experienced and flexible individual who would be comfortable working on multiple projects at once, with fluid prioritization to enable aggressive timelines. This position is for a lab-based scientific role and requires excellent scientific judgement, independence, rigor, and thorough record-keeping. Vaxcyte is seeking a flexible and collaborative Scientist comfortable managing multiple priorities in a fast-paced development environment. This role is predominantly lab-based and requires strong scientific judgment, independence in experimental execution, rigor in data analysis, and meticulous record keeping.
Requirements
- MS degree in Chemistry, Biochemistry, or related field with minimum 5 years of relevant industry experience, or BS degree with minimum 8 years of relevant industry experience.
- At least 2 years of experience in an analytical development or quality control role.
- Prior experience running colorimetric assays is required.
- Prior experience with SEC-MALS is required.
- Prior experience with SDS-PAGE is required.
- Excellent attention to detail, organizational skills, and record-keeping abilities.
- Ability to work both independently and collaboratively in a fast-paced environment.
- Commitment to integrity, professionalism, and safety in all aspects of work.
Nice To Haves
- Experience in analyzing vaccine and adjuvant-containing formulations is a plus.
Responsibilities
- Execute routine and non-routine analysis of internal release, development, and stability samples using a variety of analytical techniques across Drug Product working groups, ensuring high-quality data generation and reporting.
- Support the execution, optimization, and continuous improvement of Vaxcyte’s internal multiplex immunoassay (MSD) assay suite, including troubleshooting assay performance, improving robustness, and supporting assay lifecycle management.
- Design, execute, and interpret experiments to support non-GxP stability studies including thermal, freeze/thaw, agitation, and container closure system evaluations for both Drug Substance and adjuvanted vaccine Drug Product materials.
- Analyze and interpret complex assay data, identify trends or deviations, and communicate findings to project teams to support development decisions.
- Contribute to method development, qualification, and technology transfer activities, including collaboration with external analytical laboratories and manufacturing CMOs.
- Author and review technical documentation including assay protocols, SOPs, reports, study plans, and technical summaries in support of development and analytical activities.
- Support the Vaxcyte PCV and VAXA1 programs through cross-functional collaboration with Drug Product Development, Formulation, Analytical Development, Quality, and external partners.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Number of Employees
101-250 employees
