Scientist I, Analytical Sciences

Editas Medicine•Cambridge, MA

17h

About The Position

At Editas Medicine, we are pioneering the possible. Our mission and commitment is to translate the power and potential of the CRISPR/Cas12a and CRISPR/Cas9 genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases. Why Choose Editas? At Editas Medicine, we’re a team of passionate problem solvers, harnessing the power and potential of CRISPR gene editing to transform the future of medicine. Driven by a shared purpose to serve people living with serious diseases, we succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, where you can operate at the forefront of gene editing, and push the boundaries of what’s possible in medicine, come join us and become an Editor! Decoding The Role: As a Scientist I, you’ll be a vital contributor to the development of cutting-edge CRISPR-based therapeutics, supporting analytical workflows that enable robust process development, product understanding, and quality control. Leveraging your expertise, you will contribute to our in vivo genome editing pipeline, leading efforts to establish a suite of high-resolution mass spectrometry assays to characterize various modalities, including oligonucleotides, mRNA, and lipids. You will work collaboratively within cross-functional teams and with external partners to meet timeline-driven project goals. Additionally, you will play a key role in building internal platform capabilities to expand our product portfolio. Characterizing Your Impact: As a Scientist I, you will:

Requirements

PhD in chemistry, biochemistry, or a related field and a minimum of 3 years of relevant experience in pharmaceuticals or biotechnology, or Master’s degree in chemistry, biochemistry, or a related field and 5+ years industry experience.
Strong foundation in the chemistry and analytical characterization of oligonucleotides and lipids.
Demonstrated expertise in mass spectrometry, including method development and application to the characterization of biological macromolecules.
Hands-on experience with spectroscopic and chromatographic techniques.
Excellent analytical thinking and problem-solving skills.
Demonstrated initiative, creativity, and ability to work efficiently and independently in a laboratory setting.
Strong organizational skills with the ability to multitask, prioritize, and adapt in a collaborative team environment.
Strong written and verbal communication skills, including the ability to deliver scientific presentations

Nice To Haves

Experience working in GMP-regulated environments.
Experience with analytical method validation.
Experience managing or working with contract organizations.
Familiarity with CRISPR-based gene editing technologies.

Responsibilities

Design, develop, and execute analytical methods and experiments with a high degree of independence to support process development, investigations, and cross-functional internal stakeholders.
Lead LC-MS method development and support the optimization, troubleshooting, and lifecycle management of other release and characterization assays for CRISPR-based therapeutics.
Collaborate effectively within a team environment to meet testing turnaround times, project milestones, and quality objectives.
Partner with external vendors and contract laboratories to develop, transfer, qualify, and implement phase-appropriate analytical methods.
Train and mentor team members as needed.
Author, review, and maintain high-quality technical protocols, reports, and electronic laboratory notebook (ELN) documentation.
Manage analytical instrumentation, including development of standard operating procedures (SOPs), execution of routine maintenance and repairs, and implementation of preventative maintenance programs.
Stay current with scientific literature related to the analytical characterization of CRISPR-based therapeutics, including oligonucleotides, mRNA, and lipid nanoparticles (LNPs).

Benefits

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy
Salary Range: $115,000 - $130,000
Pay Transparency Editas Medicine is committed to transparency and accuracy in our hiring practices. The anticipated salary range for each position is posted within the role. The final salary offer will be determined based on a comprehensive assessment of the candidate's qualifications, including education, training, and relevant experience. Additional factors such as external market conditions, the role's criticality, and internal equity will also be considered. Editas Medicine's compensation philosophy ensures fair and equitable pay practices.

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