Scientist Cellular Immunology

Pfizer • Pearl River, NY

399d • $74,900 - $124,800

About The Position

As a Scientist in Cellular Immunology at Pfizer, you will play a crucial role in the Vaccine Research and Development team, focusing on the preclinical evaluation and early clinical development of candidate vaccines. This laboratory-based position requires advanced knowledge of cellular immune responses and molecular biology techniques, with a strong emphasis on compliance and quality in all work performed. Your expertise will contribute to the development of innovative therapies that aim to improve patient outcomes globally.

Requirements

• Bachelor's degree in biology, Biotechnology, Microbiology, Immunology, Life Sciences or related discipline with 6+ years of experience in immune-related assays and molecular biology techniques, or MS in related discipline with 4+ to 6 years of experience.
• Demonstrated proficiency in a wide range of immune assays and cellular techniques, including mammalian cell culture and multicolor flow cytometry.
• Experience with a broad variety of molecular biology and analytical techniques.
• Mastery of aseptic technique and familiarity with BSL2 safety practices.
• Ability to perform experimental design, data analysis, and interpretation of results.
• Proficiency with personal computers, including Excel, PowerPoint, and relevant scientific software.
• Strong motivation to learn new skills and adapt to challenges.

Nice To Haves

• Knowledge of T cell biology with expertise in T cell-based functional assays.
• Hands-on experience with NGS assay development and sequencing.
• Pharmaceutical and biotech experience.
• Experience working in a cGLP-compliant environment.

Responsibilities

• Support the preclinical evaluation and early clinical development of candidate vaccines.
• Develop and perform various assays to monitor cellular immune responses using flow cytometry and cytokine detection assays.
• Conduct RNA/DNA isolation from primary cells, cell lines, and tissue samples.
• Perform multi-color flow cytometry staining and analyze flow cytometry data.
• Execute ELISpot/FluoroSpot-based assays to measure immune responses to vaccine candidates.
• Maintain suspension and adherent cell lines and design experiments to address research questions.
• Prepare samples for next-generation sequencing (NGS) to characterize immune transcriptional signatures.
• Document experiments in an electronic notebook and contribute to drafting protocols and reports.
• Manage timelines and deliverables for various projects and assist in sourcing laboratory reagents.

Benefits

• 401(k) plan with Pfizer Matching Contributions
• Paid vacation, holiday, and personal days
• Paid caregiver/parental and medical leave
• Health benefits including medical, prescription drug, dental, and vision coverage
• Participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Chemical Manufacturing
• Education Level: Bachelor's degree