Scientist, Cell Therapy Discovery

AstraZeneca • Gaithersburg, MD

58d • Onsite

About The Position

Are you ready to push the boundaries of science and transform the lives of patients living with cancer? We are seeking a highly motivated and independent Scientist with expertise in Computational Biology applied to Cellular Therapy, Immunology, and/or Immuno-Oncology. Join our rapidly growing Cell Therapy Team and contribute to the advancement of innovative Cell Therapy products. In this role, you will develop advanced computational models using large-scale omic datasets, design and conduct laboratory experiments, and generate and interpret scientific data in a collaborative environment. The position is based in Gaithersburg, MD. AstraZeneca offers an unparalleled opportunity to work with one of the broadest and deepest Oncology pipelines in the industry. Our science-driven approach empowers us to make bold moves that transform cancer treatment and improve patient outcomes. Collaborate with top experts globally and engage with diverse functions to solve varied and interesting problems. Our commitment to patients is embedded in our pioneering spirit, driving us to challenge norms and innovate at pace. Ready to make a difference? Apply now to join our team!

Requirements

• BS in relevant disciplines or equivalent experience (e.g., Bioinformatics, Systems Biology, Applied Mathematics, Statistics, Data Science, Computer Science).
• Minimum of 2 years of experience in Cellular Therapy, Immunology, Immuno-Oncology, Computational Biology, and/or Data Science.
• Proficiency in Python and/or R.
• Prior experience in UNIX-based systems, high-performance computing (e.g., SLURM), and large-scale data management.
• Expertise in omics technologies, capable of processing large-scale biological datasets (e.g., single-cell/spatial transcriptomics, in-house proprietary data sources such as in vitro or in vivo data).
• Deep understanding of AI, predictive modeling, and statistical methods applied to training machine learning models.
• Hands-on expertise in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, cytokine measurement, and multi-parameter flow cytometry.
• Ability and motivation to drive projects to completion in a team environment.

Nice To Haves

• Experience in drug development in an industry setting.

Responsibilities

• Plan, conduct, and troubleshoot discovery research experiments within a team environment.
• Assess and report data with a clear understanding of its implications within the overall context of the project; independently formulate conclusions and determine future experiments.
• Design, develop, and deploy AI-driven machine learning and deep learning models to extract knowledge and insights from structured and unstructured data sources relevant to the development of new therapies.
• Provide technical instruction to the team and allocate administrative work where possible.
• Work collaboratively in a matrix environment.
• Prepare and deliver presentations within the Cell Therapy Unit and across other functions.
• Ensure own work, and work of peers, are compliant with relevant internal AstraZeneca standards and external regulations.

Benefits

• Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees