Scientist, Cell Pharmacology

Merck • Boston, MA

2d • Hybrid

About The Position

The Cell Pharmacology group in Department of Quantitative Biosciences is seeking a highly motivated Scientist with a background in immunology and oncology assays to join our Company's Research Laboratories in Boston. The primary responsibilities of the successful candidate will be to develop and characterize novel in vitro and ex vivo translational pharmacology assays to support autoimmune and cancer projects.
These new assays will capture features of human biology to improve preclinical translation to the clinical efficacy.

Requirements

• Proficiency in cell culture, passaging and harvesting.
• Basic knowledge of lab automation and plate readers with an ability to propose new approaches and experimental designs as needed.
• Experience with medium to high throughput assay-related data analysis and an appreciation for the related quantitative and statistical concepts.
• Candidate should be a strong team player working across the organization with ability to adapt for changing priorities.
• Excellent oral and written communication skills.
• Passion for innovation and problem solving.
• A master’s in a relevant field (e.g. Biochemistry, Biology, Biotechnology, Molecular and Cell Biology, Pharmacology; Pharmaceutical Sciences) with hands-on experience implementing and interpreting immunoassays involving blood and primary cell culture, flow cytometry, qPCR, ELISA, and major platforms such as Meso Scale Discovery and Alphalisa OR a bachelor’s degree with 3+ years of hands-on relevant laboratory experience.

Responsibilities

• Maintenance and propagation of cell lines, primary cell isolation and culture
• Develop screening assays to support therapeutic programs independently or in collaboration with senior scientists in the lab, execute assays at medium to high throughput, interpret and analyze the results of experiments, and successfully transfer assays onto automation platforms as needed.
• Interpret data and communicate results to stakeholders and management in timely manner.
• Meet project milestones and timelines.
• Conduct studies for biomarker identification and mechanism of action studies as needed to understand pharmacology.
• Implement novel technologies and approaches to solve program objectives and issues.
• Document protocols and results, comply with all laboratory safety and environmental requirements.
• Take on increasing responsibility within the Quantitative Biosciences group and on project teams as your skills develop.
• Collaborate across our global Quantitative Biosciences and other partner networks to develop capabilities, advance therapeutic programs and grow our scientific capital.

Benefits

• The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
• We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees