Scientist, Cancer Modeling

Cloverleaf BioNew Haven, CT
1d

About The Position

We are seeking an experienced In Vivo Scientist to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics. Your responsibilities will include designing and executing in house animal experiments in mice, proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs, performing cell culture experiments with lead candidate RNAs to predict in vivo outcomes, and providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics.

Requirements

  • PhD in Cancer Biology, Molecular Biology, or related fields.
  • Strong problem solving skills
  • Demonstrated ability to independently plan and execute in-vivo studies, data analysis and interpretation.
  • Experience with mouse models of disease (preferably oncology)
  • Skilled in mammalian cell culture, passaging/seeding cells, etc.

Nice To Haves

  • Research experience in RNA biology and/or RNA modifications field.
  • Experience with therapeutic development.
  • Experience with design/development RNA therapeutics and lipid nanoparticles.
  • Previous experience selecting and overseeing work at CROs.

Responsibilities

  • designing and executing in house animal experiments in mice
  • proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs
  • performing cell culture experiments with lead candidate RNAs to predict in vivo outcomes
  • providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics

Benefits

  • Competitive salary commensurate with experience and strong equity incentives.
  • Medical, dental, and vision coverage.
  • Brand new lab space in BioLabs New Haven in downtown New Haven, close to the Yale Shuttle, I-95/91 and Metro North.
  • We will provide a stimulating, collegial, and fast-paced environment.
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