Scientist - Analytical Development, Gene Therapy
About The Position
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. At Lilly Gene Therapy, we are developing a pipeline of gene therapies to slow or stop the underlying disease process for patients with genetic disorders, employing recent breakthroughs in human genetics to identify potential disease-modifying targets. Our programs use a precision medicine approach targeting patient populations with urgent unmet needs. The Analytical Development team is a tight-knit group of energetic, inquisitive, fun, and motivated individuals responsible for developing and running robust and innovative analytical methods to support internal and external manufacturing processes, while staying at the forefront of industry standards. We are seeking a motivated individual to take ownership of established molecular biology assays and contribute to the development of new innovative assays for testing gene therapy drug candidates.
Requirements
- BS or MS with 2-3+ years of lab experience with molecular biology techniques
Nice To Haves
- Lab skills which may include qPCR/ddPCR, next-generation sequencing, Sanger sequencing, gel/capillary electrophoresis, SDS-PAGE/Western blot, or others.
- Excellent pipetting technique and general lab skills.
- Assay development experience.
- Understanding of analytical method lifecycle of development, qualification, validation, and documentation is a plus.
- Prior experience with AAVs is a plus.
- Strong organizational and problem-solving skills and attention to detail.
- A passion for learning, understanding, and advancing science.
- Motivation to learn new skills both inside and outside the lab.
- Ability to work independently and in a dynamic team environment.
- Excellent verbal and written communication skills.
Responsibilities
- Perform testing in support of our internal programs using techniques such as ddPCR, agarose and capillary gel electrophoresis, Sanger sequencing, and NGS.
- Analyze, document, and report data in a prompt manner.
- Contribute to all aspects of analytical assay development, from design to qualification, for our gene therapy drugs.
- Contribute to the development and qualification of new molecular bioassays, including titer, genomic integrity, and next-generation sequencing assays.
- Perform routine testing for lot release, stability, compatibility and other studies.
- Write technical reports and SOPs.
- Communicate data within the group as well as across functions.
Benefits
- Company bonus (depending, in part, on company and individual performance)
- Company-sponsored 401(k)
- Pension
- Vacation benefits
- Medical benefits
- Dental benefits
- Vision benefits
- Prescription drug benefits
- Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- Life insurance and death benefits
- Certain time off and leave of absence benefits
- Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Number of Employees
5,001-10,000 employees
