Scientific Operations In Vivo Head, San Diego site

Crown Bioscience

About The Position

The Scientific Operations In Vivo Head at San Diego site will serve as a strategic scientific leader, overseeing the daily management of scientific and technical operations teams. This role ensures the successful execution of external studies with the highest standards of scientific and technical excellence. The position also plays a key role in advancing company growth through support of business development initiatives and driving innovation by contributing to research and development activities.

Requirements

Candidates must have extensive relevant industry experience including evidence for scientific leadership in the design and execution of complex studies aimed at non-clinical testing in animal models of disease.
Ph.D. in Pharmacology, Oncology, Cancer Biology, or related field
15+ years of relevant industry experience, including preclinical oncology model systems.
Ability to lead employees to assure company goals and results are met.
Strong interpersonal skills to work effectively in a team setting/matrix-type organization
Understands the drug development process from pre-IND through BLA
Highly organized, outcome-oriented, self-motivated performer
Experience with regulatory-compliant animal study practices (IACUC standards, AAALAC accreditation).

Nice To Haves

Prior experience working in a fast paced Contract Research Organization
Familiarity with patient-derived xenograft (PDX), cell line-derived xenograft (CDX), syngeneic, and humanized mouse models.
Experience integrating molecular characterization (RNA-seq, proteomics) into in vivo pharmacology programs is a plus.
Prior experience in business development or client-facing scientific roles.

Responsibilities

Oversee integrated drug discovery programs by collaborating with clients and cross-functional internal teams, delivering scientific and operational recommendations, and optimizing program workflows to ensure effective execution and strategic growth.
Direct all daily in vivo pharmacology operations, ensuring scientific excellence, operational efficiency, and adherence to high ethical and quality standards.
Manage a team of scientists and research associates dedicated to preclinical in vivo studies, fostering professional development and a culture of innovation.
Responsible for scientific and technical operations training programs.
Help scientists with trouble shooting and client communication. Required to have active client interaction and BD support, including but not limited to teleconferences and presentations to clients, hosting client visits
Drive continuous improvement in study protocols, data quality, and operational workflows to maintain industry-leading standards.
Collaborate with BD and marketing teams by offering scientific guidance and leveraging drug discovery experience.
As the scientific and technical leader, participate in compliance management, animal health and regulatory aspects of scientific operations.
As an extended part of the research team, participates in the company's research program.
Take on study director role for major accounts if needed, and be responsible for all duties involved in external studies assigned.
Collaborate closely with other departments and functions to support overall company tasks.
Actively involved in scientific writing, including abstract/poster/ppt/manuscripts preparation, etc.
Conduct work activities in compliance with all relevant regulations including ethics, environmental health and safety, financial, human resources, SOPs, and general business policies, requirements and objectives
Maintains staff by recruiting, selecting, orienting, and training employees; developing personal growth opportunities.
Accomplishes staff job results by coaching, counseling, and disciplining employees; planning, monitoring, and appraising job results; conducting training; implementing enforcing systems, policies, and procedures.
Plan, oversight, and maintenance of department budget.